Acellular Dermal Matrix Graft for Gingival Augmentation: A Preliminary Clinical, Histologic, and Ultrastructural Evaluation

Scarano, Antonio; Barros, Raquel Rezende Martins de; Iezzi, Giovanna; Piattelli, Adriano; Novaes, Arthur B.

doi:10.1902/jop.2009.080326

Cited by 74 publications

(64 citation statements)

References 25 publications

(31 reference statements)

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“…These results were all confirmed by a further histological study [26]. During the first week of healing they noticed a tissue remodelling due to phagocytosis of pre-existing collagen fibers by macrophages.…”

Section: Discussionsupporting

confidence: 65%

Use of a Collagen Matrix as a Substitute for Free Mucosal Grafts in Pre-Prosthetic Surgery: 1 Year Results From a Clinical Prospective Study on 15 Patients

Maiorana

Beretta

Pivetti

et al. 2016

TODENTJ

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Background:The presence of keratinized tissue around dental implants is more than desirable either from a functional and aesthetic point of view, making soft tissue grafting a common practice in implant rehabilitation. Autogenous soft tissue grafting procedures are usually associated with high morbidity. Aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants.Methods:15 consecutive patients underwent a vestibuloplasty and grafting, both in the mandible and the maxilla, with a collagen matrix.Results:The primary endpoint was to evaluate the resorption of the graft along with the re-epithelization grafted area. The percentage of the resorption was 44,4%, with a mean gain in vestibular height of 3 mm. Secondary endpoints evaluated the clinical appearance, the hemostatic effect and the post-operative pain. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection were noted.Conclusion:This study showed that the used collagen matrix can find major interest in those patients who need a greater aesthetic outcome as the matrix has a perfect integration with the surrounding tissues. Furthermore it is strongly recommended for those patients who can bear little pain.Clinical Significance:Post-operative morbidity of autologous grafts is the biggest concern of this type of surgery. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery.The present study showed the efficacy of a collagen matrix as this kind of substitute.

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Section: Discussionsupporting

confidence: 65%

Use of a Collagen Matrix as a Substitute for Free Mucosal Grafts in Pre-Prosthetic Surgery: 1 Year Results From a Clinical Prospective Study on 15 Patients

Maiorana

Beretta

Pivetti

et al. 2016

TODENTJ

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show abstract

“…Its autogenous character, ease of technique, cost effectiveness and together with the possibility of implementation in a group of teeth leads FGG to be accepted as the golden standard to increase attached gingiva dimensions [11]. There are several other techniques tried and amongst them, Acellular Dermal Matrix (ADM) allograft is emerging for its advantage of avoiding palatal complications [12,13]. However, comparative studies evaluating ADM and free gingival graft show that ADM allograft exhibits more shrinkage and are less effective and predictable than an autogenous FGG [12,14].…”

Section: Discussionmentioning

confidence: 99%

Epithelized Free Autograft-A Case Report Series with Different Healing Outcomes

Goel¹

2017

IOSR JDMS

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“…ADM has received attention because of its histocompatibility and capability in reducing scar tissue formation. Historically, following its first use in burn surgery in 1992, ADM was introduced to periodontal surgery in 1994, as an alternative to the autogenous free gingival graft to achieve increased attached keratinized gingiva around natural teeth and to repair oral and gingival defects and recession as well as meninx reparation due to its low immune responses 22,30 . The application of ADM suffers from a limited supply of sources, expense, antigenicity and predisposition to infection.…”

Section: Discussionmentioning

confidence: 99%

Assessment of silk fibroin for the repair of buccal mucosa in a rat model

Zhang¹,

Yang²,

Xiang³

et al. 2012

International Journal of Oral and Maxillofacial Surgery

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Acellular Dermal Matrix Graft for Gingival Augmentation: A Preliminary Clinical, Histologic, and Ultrastructural Evaluation

Abstract: The acellular dermal matrix graft seemed to be an easily handled material for use in keratinized tissue augmentation that, in humans, was substituted and completely reepithelialized in 10 weeks according to histologic and ultrastructural results.

Cited by 74 publications

References 25 publications

Use of a Collagen Matrix as a Substitute for Free Mucosal Grafts in Pre-Prosthetic Surgery: 1 Year Results From a Clinical Prospective Study on 15 Patients

Use of a Collagen Matrix as a Substitute for Free Mucosal Grafts in Pre-Prosthetic Surgery: 1 Year Results From a Clinical Prospective Study on 15 Patients

Epithelized Free Autograft-A Case Report Series with Different Healing Outcomes

Assessment of silk fibroin for the repair of buccal mucosa in a rat model

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