ACE I/D Gene Polymorphism in Athletes of Various Sports Disciplines

Abstract

Purpose. Genetic factors play an important role in physical performance. In this study, the polymorphism of the angiotensinconverting enzyme gene (ACE) was analyzed in relation to the level of physical fitness, measured by maximal oxygen uptake (VO 2max ). Methods. Molecular genetic research on the ACE gene was carried out on a group of 154 men and 85 women. All of the subjects were Polish students at the University School of Physical Education in Poznań and included professional athletes representing various sport disciplines and levels of fitness. Results. Allele I was found to have an advantageous effect on higher maximal oxygen uptake values and, in addition, a characteristic distribution of genotypes was found, where allele II was more common in individuals practicing aerobic sports and allele DD in individuals training anaerobic disciplines. Conclusion. No significant associations were found between I/D polymorphism in the ACE gene and VO 2max values but certain tendencies were found for those individuals with the ACE II genotype.

La Nueva Frontera De La Preparación Deportiva, La Genética Y El Polimorfismo Ace I/D en Atletas De Resistencia

“…La gran mayoría de las investigaciones sobre el polimorfismo ACE I/D, deducen la relación positiva entre el polimorfismo con el estatus y el rendimiento deportivo, a partir de la comparación de las frecuencias genotípicas y alélicas, entre los grupos de atletas y los grupos controles. En este aspecto, concluyen que una mayor frecuencia del genotipo II y el alelo I en la población atleta, en relación con los grupos controles, es un indicador de la relación del polimorfismo con el rendimiento (en este caso con el fenotipo de la resistencia) (Holdys et al 2011). Ahora bien, nuestros resultados coinciden con esta hipótesis.…”

The relationship between CA repeat polymorphism of the <i>IGF-1</i> gene and the structure of motor skills in young athletes

“…The way in which an organism adapts to physical exertion depends, among others, on the regulation of many genes' expression e.g. IGF1, ACTN3, PPAR delta, ACE (Karlowatz et al, 2011;Jung et al, 2016;Maciejewska-Karłowska, 2013;Orysiak et al, 2015;Holdys et al, 2011). Their polymorphism turned out to be an important factor that influences the level of physical performance (Scheinowitz et al, 2003).…”

Atletik Performans ve Spor Genetiği

“…Öte yandan, II genotipli bireyler daha düşük bir ACE serum konsantrasyonuna sahiptir ve orta ve uzun mesafe koşuları, yarış yürüyüşleri ve kayak gibi dayanıklılık ile ilgili disiplinlerde daha fazla başarıya sahiptir [20]. Literatür bilgisine paralel olarak Shahmoradi…”