Accurate Preoperative Diagnosis of Ovarian Pregnancy with Transvaginal Scan

Gupta, Nalini; Gupta, Anu; Onyema, Godwin; Pantofel, Yelena; Ying, Shan-Ching; Garon, Jack; Lampley, Charles E.; Josef, Blankstein

doi:10.1155/2012/934571

Cited by 11 publications

(13 citation statements)

References 10 publications

(16 reference statements)

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“…The histopathology findings of squamous cell carcinoma as the most common type of cervical cancer in our study is similar to studies done in Kenya, Uganda and South Africa in which as high as 80% of cases had squamous cell carcinoma [ 13 , 16 - 18 ]. In contrast, the finding of non-squamous cervical cancer in this study of just 8.7% is lower than the 11% reported in Nigeria [ 19 ].…”

Section: Discussionsupporting

confidence: 89%

HIV serostatus and tumor differentiation among patients with cervical cancer at Bugando Medical Centre

et al. 2012

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BackgroundEvidence for the association between Human immunodeficiency virus infection and cervical cancer has been contrasting, with some studies reporting increased risk of cervical cancer among HIV positive women while others report no association. Similar evidence from Tanzania is scarce as HIV seroprevalence among cervical cancer patients has not been rigorously evaluated. The purpose of this study was to determine the association between HIV and tumor differentiation among patients with cervical cancer at Bugando Medical Centre and Teaching Hospital in Mwanza, North-Western Tanzania.MethodsThis was a descriptive analytical study involving suspected cervical cancer patients seen at the gynaecology outpatient clinic and in the gynaecological ward from November 2010 to March 2011.ResultsA total of 91 suspected cervical cancer patients were seen during the study period and 74 patients were histologically confirmed with cervical cancer. The mean age of those confirmed of cervical cancer was 50.5 ± 12.5 years. Most patients (39 of the total 74–52.7%) were in early disease stages (stages IA-IIA). HIV infection was diagnosed in 22 (29.7%) patients. On average, HIV positive women with early cervical cancer disease had significantly more CD4+ cells than those with advanced disease (385.8 ± 170.4 95% CI 354.8-516.7 and 266.2 ± 87.5, 95% CI 213.3-319.0 respectively p = 0.042). In a binary logistic regression model, factors associated with HIV seropositivity were ever use of hormonal contraception (OR 5.79 95% CI 1.99-16.83 p = 0.001), aged over 50 years (OR 0.09 95% CI 0.02-0.36 p = 0.001), previous history of STI (OR 3.43 95% CI 1.10-10.80 p = 0.035) and multiple sexual partners OR 5.56 95% CI 1.18-26.25 p = 0.030). Of these factors, only ever use of hormonal contraception was associated with tumor cell differentiation (OR 0.16 95% CI 0.06-0.49 p = 0.001). HIV seropositivity was weakly associated with tumor cell differentiation in an unadjusted analysis (OR 0.21 95% CI 0.04-1.02 p = 0.053), but strong evidence for the association was found after adjusting for ever use of hormonal contraception with approximately six times more likelihood of HIV infection among women with poorly differentiated tumor cells compared to those with moderately and well differentiated cells (OR 5.62 95% CI 1.76-17.94 p = 0.004).ConclusionResults from this study setting suggest that HIV is common among cervical cancer patients and that HIV seropositivity may be associated with poor tumour differentiation. Larger studies in this and similar settings with high HIV prevalence and high burden of cervical cancer are required to document this relationship.

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Section: Discussionsupporting

confidence: 89%

HIV serostatus and tumor differentiation among patients with cervical cancer at Bugando Medical Centre

et al. 2012

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“…5 Other risk factors for OEP include a history of endometriosis, ovulation induction and other assisted reproductive technologies, and advanced maternal age. 1,6,7 The clinical presentation of OEP is similar to other ectopic pregnancies, namely, mild-to-moderate pelvic pain, vaginal bleeding, abnormal beta-hCG levels, and a palpable adnexal mass. [6][7][8] The patient in this case had a few risk factors, including being of advanced maternal age and the use of ovulation induction medication.…”

Section: Discussionmentioning

confidence: 97%

“…1,6,7 The clinical presentation of OEP is similar to other ectopic pregnancies, namely, mild-to-moderate pelvic pain, vaginal bleeding, abnormal beta-hCG levels, and a palpable adnexal mass. [6][7][8] The patient in this case had a few risk factors, including being of advanced maternal age and the use of ovulation induction medication. Differential diagnoses of an OEP can include a corpus luteum cyst, a hemorrhagic ovarian cyst, appendicitis, tubal ectopic, or an early or failed intrauterine pregnancy (IUP).…”

Section: Discussionmentioning

confidence: 97%

Sonographic Detection of Ovarian Ectopic Pregnancy

Kadau

2016

Journal of Diagnostic Medical Sonography

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Sonography is the imaging modality of choice to evaluate suspected intrauterine and extrauterine pregnancies. Determining the anatomic location of an ectopic pregnancy can be challenging, particularly when the ectopic is located external to the fallopian tube. Ovarian ectopic pregnancy is one of the rarest forms of nontubal ectopics. This report documents one such uncommon case of ovarian pregnancy in a woman presenting with light vaginal bleeding in early pregnancy, with subsequent rupture and laparotomy. Histopathologic analysis confirmed the diagnosis of ovarian ectopic pregnancy.

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“…Comstock et al, observed ultrasonography of six ovarian pregnancy patients and concluded the presence of hypoechoic ring on or within the surface of ovary in five out of six patients. 13 Corpus luteum and ovarian pregnancy are differentiated on the basis of echogenocity of hypoechoic ring. The corpus luteum appears less echogenic than rest of ovary while the ovarian pregnancy is more echogenic than rest of the ovary.…”

Section: Discussionmentioning

confidence: 99%

Advanced ovarian pregnancy: an elusive diagnosis

Bhanupriya¹

2019

Int J Reprod Contracept Obstet Gynecol

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Primary ovarian ectopic is a rare variant of ectopic pregnancies. It is commonly confused with tubal pregnancy aborted over ovary, hemorrhagic ovarian cyst, ruptured corpus luteal cyst. The women with ovarian ectopic generally presents early because of early onset hemorrhage in ovary. This is a rare case where woman with ectopic pregnancy presents at 13 weeks. The clinical picture is also highly unusual with just spotting and fainting attacks at the end of first trimester to make a diagnosis of ectopic pregnancy. The laparotomy done showed an unruptured ovarian ectopic pregnancy and with 350 cc hemoperitoneum. Salpingoopherectomy was done and the ectopic mass was removed as hardly any ovarian tissue was left to conserve the ovary. Hence, clinicians should be cautious enough to keep a differential diagnosis of ectopic even at advanced gestation.

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Accurate Preoperative Diagnosis of Ovarian Pregnancy with Transvaginal Scan

Cited by 11 publications

References 10 publications

HIV serostatus and tumor differentiation among patients with cervical cancer at Bugando Medical Centre

HIV serostatus and tumor differentiation among patients with cervical cancer at Bugando Medical Centre

Sonographic Detection of Ovarian Ectopic Pregnancy

Advanced ovarian pregnancy: an elusive diagnosis

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