Accurate lesion localisation facilitates nephron sparing surgery in reninoma patients: case report and discussion

Mondschein, Romy; Kwan, Edward; Abou-Seif, Claire; Rajarubendra, Nieroshan

doi:10.1016/j.eucr.2022.102069

Cited by 2 publications

(1 citation statement)

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“…Some reninomas display low enhancement compared to the renal parenchyma and can even be mistaken for a cyst, 22,23 possibly explained by local vasoconstrictor effect of angiotensin II and/or a lack of neovascular development within the tumour. 22,24 In other cases, mild contrast enhancement is seen, especially in the late phase of imaging, [25][26][27][28][29][30] as in our Cases 2 and 3. MRI can also be used to identify reninomas and is often preferred in younger patients.…”

Section: Discussionsupporting

confidence: 65%

Diagnostic challenges in patients with reninomas and extrarenal renin‐producing tumours

Fabian,

Ragnarsson,

Prazic

et al. 2024

Clinical Endocrinology

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Renin‐secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work‐up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin‐producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work‐up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose‐positron emission tomography‐CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.

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