Accurate helical cone-beam CT reconstruction with redundant data

Schöndube, Harald; Stierstorfer, Karl; Noo, Frédéric

doi:10.1088/0031-9155/54/15/001

Cited by 8 publications

(11 citation statements)

References 30 publications

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“…However, the utilization of those redundant data is desirable in terms of reducing image noise. Therefore, appropriately using all the available data in image reconstruction is essential to noise and dose reduction [85–87]. …”

Section: General Dose-reduction Strategiesmentioning

confidence: 99%

Radiation dose reduction in computed tomography: techniques and future perspective

Yu¹,

Liu²,

Leng³

et al. 2009

Imaging in Medicine

328

215

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Despite universal consensus that computed tomography (CT) overwhelmingly benefits patients when used for appropriate indications, concerns have been raised regarding the potential risk of cancer induction from CT due to the exponentially increased use of CT in medicine. Keeping radiation dose as low as reasonably achievable, consistent with the diagnostic task, remains the most important strategy for decreasing this potential risk. This article summarizes the general technical strategies that are commonly used for radiation dose management in CT. Dose-management strategies for pediatric CT, cardiac CT, dual-energy CT, CT perfusion and interventional CT are specifically discussed, and future perspectives on CT dose reduction are presented.

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Section: General Dose-reduction Strategiesmentioning

confidence: 99%

Radiation dose reduction in computed tomography: techniques and future perspective

Yu¹,

Liu²,

Leng³

et al. 2009

Imaging in Medicine

328

215

View full text Add to dashboard Cite

show abstract

“…The notation is exactly the same as that used in Ref. [13] where more extensive details can be found.…”

Section: Dbp-ht On M-linesmentioning

confidence: 99%

“…In Ref. [13], we have shown that this property of the DBP can be employed to efficaciously reduce image noise without significantly changing the spatial resolution. The reconstruction procedure can be described as follows:…”

Section: Dbp-ht On M-linesmentioning

confidence: 99%

“…[13], we have introduced a TES method dubbed “M-line DBP-HT” that is capable of beneficially using all detector data at maximum pitch. The method operates by using a differentiated backprojection (DBP) followed by an inverse Hilbert transform (HT) and is capable of processing redundant data by working on M-lines, which are lines connecting a source position with any point on the detector (“M-line” is an acronym for “measured line”).…”

Section: Introductionmentioning

confidence: 99%

“…[13] that is capable of handling the problem of interrupted illumination and is thus able to use all measured data at arbitrary pitch.…”

Section: Introductionmentioning

confidence: 99%

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Exact efficient handling of interrupted illumination in helical cone-beam computed tomography with arbitrary pitch

Schöndube

Stierstorfer

Noo

2010

Tinshhua Sci. Technol.

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We present a theoretically-exact and stable computed tomography (CT) reconstruction algorithm that is capable of handling interrupted illumination and therefore of using all measured data at arbitrary pitch. This algorithm is based on a differentiated backprojection (DBP) on M-lines. First, we discuss the problem of interrupted illumination and how it affects the DBP. Then we show that it is possible to take advantage of some properties of the DBP to compensate for the effects of interrupted illumination in a mathematically exact way. From there, we have developed an efficient algorithm which we have successfully implemented. We show encouraging preliminary results using both computer-simulated data and real data. Our results show that our method is capable of achieving a substantial reduction of image noise when decreasing the helix pitch compared with the maximum pitch case. We conclude that the proposed algorithm defines for the first time a theoretically-exact and stable reconstruction method that is capable of beneficially using all measured data at arbitrary pitch.

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Advances in micro-CT imaging of small animals

Clark

Badea

2021

Physica Medica

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Micron-scale computed tomography (micro-CT) imaging is a ubiquitous, cost-effective, and non-invasive three-dimensional imaging modality. We review recent developments and applications of micro-CT for preclinical research. Methods: Based on a comprehensive review of recent micro-CT literature, we summarize features of state-of-theart hardware and ongoing challenges and promising research directions in the field. Results: Representative features of commercially available micro-CT scanners and some new applications for both in vivo and ex vivo imaging are described. New advancements include spectral scanning using dual-energy micro-CT based on energy-integrating detectors or a new generation of photon-counting x-ray detectors (PCDs). Beyond two-material discrimination, PCDs enable quantitative differentiation of intrinsic tissues from one or more extrinsic contrast agents. When these extrinsic contrast agents are incorporated into a nanoparticle platform (e.g. liposomes), novel micro-CT imaging applications are possible such as combined therapy and diagnostic imaging in the field of cancer theranostics. Another major area of research in micro-CT is in x-ray phase contrast (XPC) imaging. XPC imaging opens CT to many new imaging applications because phase changes are more sensitive to density variations in soft tissues than standard absorption imaging. We further review the impact of deep learning on micro-CT. We feature several recent works which have successfully applied deep learning to micro-CT data, and we outline several challenges specific to micro-CT. Conclusions: All of these advancements establish micro-CT imaging at the forefront of preclinical research, able to provide anatomical, functional, and even molecular information while serving as a testbench for translational research.

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Accurate helical cone-beam CT reconstruction with redundant data

Cited by 8 publications

References 30 publications

Radiation dose reduction in computed tomography: techniques and future perspective

Radiation dose reduction in computed tomography: techniques and future perspective

Exact efficient handling of interrupted illumination in helical cone-beam computed tomography with arbitrary pitch

Advances in micro-CT imaging of small animals

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