Accuracy of trans-abdominal ultrasound in a simulated massive acute overdose

Sullivan, Scott; Wolterstorff, Cameron; Johnson, Jeremy; Ball, Vincent; Skinner, Carl; Bothwell, Jason

doi:10.1016/j.ajem.2016.04.030

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…The potential application of ultrasound in the detection of pills in the stomach has been previously described [15]. The sensitivity and specificity of gastric ultrasound in the visualization of ingested pills after 60 minutes following ingestion are 20.8% and 79.1%, respectively [15,16]. The presence of food or lack of fluid inside the stomach, the dissolution of the tablets, or their passage to the pylorus may impair the visualization of ingested pills using gastric ultrasound, and gastric lavage may not show benefit [16].…”

Section: Discussionmentioning

confidence: 99%

“…The sensitivity and specificity of gastric ultrasound in the visualization of ingested pills after 60 minutes following ingestion are 20.8% and 79.1%, respectively [15,16]. The presence of food or lack of fluid inside the stomach, the dissolution of the tablets, or their passage to the pylorus may impair the visualization of ingested pills using gastric ultrasound, and gastric lavage may not show benefit [16]. Also, in this case, toxicity was already established, and gastric lavage may have had little effect by the time the patient was being treated in hospital.…”

Section: Discussionmentioning

confidence: 99%

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Successful Outcome Following Intravenous Lipid Emulsion Rescue Therapy in a Patient with Cardiac Arrest Due to Amitriptyline Overdose

2020

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Management of emergency care Background:The management of patients with tricyclic antidepressant drug overdose can be a challenge for the emergency department physician. Tricyclic antidepressants block alpha-adrenergic receptors and the anticholinergic effects may lead to cardiotoxicity, resulting in arrhythmias and hypotension that can lead to patient mortality. This report is of a case of a 28-year-old woman who presented with cardiac arrest due to amitriptyline overdose and who responded to intravenous lipid emulsion (ILE) therapy. Case Report:A 28-year-old woman was admitted to the emergency department with amitriptyline overdose. She suffered a cardiac arrest followed by cardiovascular and neurological complications. Hypotension and lack of a pulse did not respond to treatment with high-dose sodium, but she stabilized following treatment with ILE. The prompt response from the emergency team guaranteed rapid intervention that may have influenced the successful results. Conclusions:Despite the frequency and severity of poisoning with tricyclic antidepressants, there is little consensus among physicians regarding patient management. This case showed the successful use of ILE as rescue therapy in a patient in cardiac arrest following amitriptyline overdose. However, the successful outcome obtained in this case is not a recommendation for the use of ILE as a first-line treatment for the management of patients with tricyclic antidepressant drug overdose. Controlled clinical studies are required to evaluate the safety and efficacy of ILE in the management of tricyclic antidepressant drug overdose.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Successful Outcome Following Intravenous Lipid Emulsion Rescue Therapy in a Patient with Cardiac Arrest Due to Amitriptyline Overdose

2020

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Ultrasound assessment of gastrointestinal luminal contents: a narrative review

Su,

Taylor,

Friedman

et al. 2024

J Ultrasound

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Gastro-intestinal ultrasound (GIUS) is a non-invasive and cost-effective tool, widely used as a first-line diagnostic method in patients presenting with abdominal complaints, especially in patients affected by inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis. In this setting, gastro-intestinal ultrasound has been especially used to evaluate the bowel wall features (thickening, stratification, vascularization) and complications related to IBD (fistulas, abscesses). Nevertheless, gastro-intestinal ultrasound can be also used to detect and evaluate the content of several segments of the gut. In fact, there is a growing interest in utilizing GIUS for suspected functional disorders, where assessing intestinal content may play a significant diagnostic role, as well as directing therapy. In our review, we provided a sonographic description of GIUS appearances of bowel content in various pathological and physiological conditions, offering potential applications in clinical practice and providing insights for further research.

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Accuracy of trans-abdominal ultrasound in a simulated massive acute overdose

Cited by 2 publications

References 7 publications

Successful Outcome Following Intravenous Lipid Emulsion Rescue Therapy in a Patient with Cardiac Arrest Due to Amitriptyline Overdose

Successful Outcome Following Intravenous Lipid Emulsion Rescue Therapy in a Patient with Cardiac Arrest Due to Amitriptyline Overdose

Ultrasound assessment of gastrointestinal luminal contents: a narrative review

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