Accuracy of pharmaceutical advertisements in medical journals

Villanueva, Pilar; Peiró, Salvador; Librero, Julián; Pereiró, I

doi:10.1016/s0140-6736(03)12118-6

Cited by 157 publications

(144 citation statements)

References 18 publications

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“…The reasons for inconsistent or somewhat consistent information found in the present study were similar to those reported in other studies in Spain: 5,23 missing information, other drugs studied, patients with conditions not investigated in the studies, statistical differences were not signifi cant, extrapolation of indications and conditions and conclusions other than those claimed in the materials. According to RDC 102/00, a it is thus characterized misleading advertising due to information omission or misinformation.…”

Section: Discussionsupporting

confidence: 82%

“…Hence, unbalanced information is usually found in advertising claims. 15,17,23 A good number of claims reviewed (67.7%) were consistent with the references because consistency was ascertained when the cited information was identifi ed regardless of any other considerations. RDC 102/00, Art.…”

Section: Discussionmentioning

confidence: 93%

“…These authors did not have access to 18% of the cited references since they were monographs or unpublished data. 23 Prescribers would fi nd even more diffi cult to have access to referenced information in drug promotional materials.…”

Section: Discussionmentioning

confidence: 99%

“…It can be noted that today pharmaceutical companies tend to provide references as marketing strategies of drug promotion. 23 Pharmaceutical companies frequently draw on randomized clinical trial studies (44.6%) published in renowned indexed medical journals, 5,23 especially intended for therapeutic choice. 21 On the other hand, 36.1% of references here studied were literature reviews, which are less recommended 21 and in general promotional claims favorably supported drug use and omitted warnings and precautions to specifi c populations stressed in the reviews.…”

Section: Discussionmentioning

confidence: 99%

“…Few studies 5,23 have addressed reliability, accuracy and truthfulness of information in drug promotional materials and their related cited references. Although it is a major issue and a requirement for complying with international recommendations, 20 The purpose of the present study was to review psychoactive drug promotional materials targeted to physicians as for consistency of information with their related references and to assess accessibility of the cited references.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Propagandas de medicamentos psicoativos: análise das informações científicas

Mastroianni¹,

Noto²,

Galduróz³

2008

Rev. Saúde Pública

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OBJECTIVE: According to the World Health Organization, medicinal drug promotion should be reliable, accurate, truthful, informative, balanced, up-to-date and capable of substantiation. The objective of the present study was to review psychoactive drug advertisements to physicians as for information consistency with the related references and accessibility of the cited references. METHODS:Data was collected in the city of Araraquara, Southeastern Brazil, in 2005. There were collected and reviewed 152 drug advertisements, a total of 304 references. References were requested directly from pharmaceutical companies' customer services and searched in UNESP (Ibict, Athenas) and BIREME (SciELO, PubMed, free-access indexed journals) library network and CAPES journals. Advertisement statements were checked against references using content analysis. RESULTS:Of all references cited in the advertisements studied, 66.7% were accessed. Of 639 promotional statements identifi ed, 346 (54%) were analyzed. The analysis showed that 67.7% of promotional statements in the advertisements were consistent with their references, while the remaining was either partially consistent or inconsistent. Of the material analyzed, an average 2.5 (1-28) references was cited per advertisement. In the text body, there were identifi ed 639 pieces of information clearly associated with at least one cited reference (average 3.5 pieces of information per advertisement). CONCLUSIONS:The study results evidenced difficult access to the references. Messages on effi cacy, safety and cost, among others, are not always supported by scientifi c studies. There is a need for regulation changes and effective monitoring of drug promotional materials.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%