Accuracy of hysteroscopic diagnosis of endometrial hyperplasia: A retrospective study of 323 patients

Garuti, Giancarlo; Cellani, Fulvia; Garzia, Delia; Colonnelli, Monica; Luerti, Massimo

doi:10.1016/j.jmig.2005.03.006

Cited by 44 publications

(28 citation statements)

References 15 publications

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“…Among patients with endometrial polyps, hyperplasia was diagnosed in 11.9% (15). Furthermore, another study found endometrial carcinoma in 3.9% of menopausal women with an endometrial polyp (16).…”

Section: Discussionmentioning

confidence: 98%

“…Restoration of reproductive ability was found to be unrelated to the size of the removed lesion (5,14). However, a statistically significant difference in pregnancy rate was found between women who underwent hysteroscopy before an IVF-embryo transfer cycle and those who did not undergo a hysteroscopy (15). Furthermore, the specific hysteroscopy procedure for polyps of different size currently is subject to debate.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Location of endometrial polyp and pregnancy rate in infertility patients

Yanaihara

Yorimitsu²,

Motoyama³

et al. 2008

Fertility and Sterility

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Location of endometrial polyp and pregnancy rate in infertility patients

Yanaihara

Yorimitsu²,

Motoyama³

et al. 2008

Fertility and Sterility

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“…The three suspected cases were not confirmed and 12 cases occurred without hysteroscopic suspicion. Several studies evaluated the accuracy of hysteroscopy in the diagnosis of endometrial hyperplasia [14][15][16][17][18][19] and all of them emphasize the lack of precise hysteroscopic criteria for hyperplasia diagnosis. In fact, our results probably underline this aspect.…”

Section: Discussionmentioning

confidence: 99%

Office Hysteroscopy After Ultrasonographic Diagnosis of Thickened Endometrium in Postmenopausal Patients

Cordeiro

Condeço

Leitão

et al. 2010

Obstetrical &Amp; Gynecological Survey

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The aim of our study was to access office hysteroscopy results in postmenopausal patients with thickened endometrium. A retrospective descriptive study was carried out on 245 postmenopausal patients submitted to office hysteroscopy after sonographic diagnosis of thickened endometrium in 20 consecutive months. Women were evaluated for age, hormonal therapy, hysteroscopic findings, procedure duration, complications and associated pain, and histological diagnosis. Patients with and without uterine bleeding were considered separately. Symptomatic patients were older and had longer procedure duration. The most frequent hysteroscopic finding was endometrial polyp in both groups. Pain was subjectively assessed in a numeric scale from 0 to 10 and median value was 4. There were no complications reported. Global neoplasia rate was 2.9% for asymptomatic patients and 16.4% for symptomatic ones (p<0.05). Thickened endometrium with postmenopausal metrorrhagia gave patients a significantly higher risk for neoplasia and hyperplasia.

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“…This case illustrates the debate found in a recently published study of 323 hyperplasias in which the criteria for hysteroscopic diagnosis were found to be inaccurate, thereby providing justifi cation for histopathologically assessing every irregularly lined or thickened endometrium. 30 Among the 399 asymptomatic patients who underwent hysteroscopy, one had complex hyperplasia with atypia and another had endometrial adenocarcinoma, together accounting for only 0.5% of the examinations performed. This is consistent with the fi ndings of Gambacciani et al, 31 who conducted 148 hysteroscopy procedures on asymptomatic patients with endometrial thickening and also found only one case of hyperplasia and one of adenocarcinoma.…”

Section: Discussionmentioning

confidence: 99%

Hysteroscopy as a standard procedure for assessing endometrial lesions among postmenopausal women

et al. 2007

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CONTEXT AND OBJECTIVES: Endometrial cancer is the most prevalent type of malignant neoplasia of the genital tract. The objective of this study was to calculate the sensitivity, specificity, accuracy and positive and negative predictive values for diagnostic hysteroscopy, in comparison with histopathological tests, for all lesions of the endometrial cavity. DESIGN AND SETTING: Retrospective descriptive study at the public tertiary-level university hospital of Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. METHODS: Diagnostic hysteroscopy was indicated in the following instances: endometrial thickness > 4 mm in asymptomatic patients; postmenopausal bleeding; and irregular endometrium or endometrium difficult to assess from ultrasound, with or without vaginal bleeding. Ultrasound evaluations were carried out no more than three months prior to hysteroscopy. RESULTS: There were 510 patients, with a mean age of 61.1 ± 2.0 years and mean time elapsed since the menopause of 12.7 ± 2.5 years. Endometrial biopsies were performed on 293 patients (57.5%). Histopathological analysis showed that 18 patients presented endometrial carcinoma or typical or atypical hyperplasia, and none of them presented endometrial thickness of less than 8 mm. No significant differences were found between the median thicknesses of the various benign lesions (p > 0.05). In our data, the sensitivity, specificity, accuracy and positive and negative predictive values for cancer or hyperplasia were 94.4%, 97.0%, 96.8%, 68% and 99.6%, respectively. CONCLUSIONS: Our results suggest that hysteroscopy is valuable as a diagnostic tool for malignant/hyperplastic and benign lesions, except for submucous myomas, for which the sensitivity was only 52.6%.

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Accuracy of hysteroscopic diagnosis of endometrial hyperplasia: A retrospective study of 323 patients

Cited by 44 publications

References 15 publications

Location of endometrial polyp and pregnancy rate in infertility patients

Location of endometrial polyp and pregnancy rate in infertility patients

Office Hysteroscopy After Ultrasonographic Diagnosis of Thickened Endometrium in Postmenopausal Patients

Hysteroscopy as a standard procedure for assessing endometrial lesions among postmenopausal women

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