Accuracy of Current Body Mass Index Obesity Classification for White, Black, and Hispanic Reproductive-Age Women

Rahman, Mahbubur; Berenson, Abbey B.

doi:10.1097/aog.0b013e3181da9423

Cited by 148 publications

(137 citation statements)

References 26 publications

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“…Overweight or obesity in adults was defined by the World Health Organization (WHO) [18] as BMI >25 kg/m² for overweight and BMI>30 kg/m² for obese. The FGS system was used to assess hair growth in 11 areas of the body.…”

Section: Inclusion Criteriamentioning

confidence: 99%

Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome

Şahin

Ural

et al. 2015

Biomol Biomed

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Polycystic ovary syndrome (PCOS) is one of the most common causes of female infertility. It affects nearly 5-10% of young women. It is characterized by the presence of hirsutism, acne, anovulation, hyperandrogenism, polycystic ovaries, and infertility [1]. Many mechanisms have been reported to be responsible for the pathophysiology of PCOS. The condition is thought to be determined by complex interactions between the hypothalamic-pituitary-ovarian or hypothalamic-pituitary-adrenal axis functions and metabolic disorders, such as obesity, insulin resistance (IR), and compensatory hyperinsulinemia [2]. PCOS increases the prevalence of hyperglycemia, hypertension, and dyslipidemia [3], increasing thus the risk of developing cardiovascular diseases [4].Nesfatin-1 (N1) is derived from nucleobindin 2 (NUCB2), which is encoded by the NUCB2 gene. It is a newly identified peptide that has 82 amino acids [5]. It is released from several tissues including forebrain, hindbrain, brainstem, spinal cord, adipose tissues [6]. It has an anorexigenic effect and plays an important role in hypothalamic pathways such as regulating food intake, energy homeostasis, water intake, and body temperature [7,8]. In addition, it exerts cardiovascular and hypertensive effects [9]. It is closely related to glucose, insulin metabolism, and IR [5,10]. Several studies have demonstrated N1 to be associated with body mass index (BMI), IR, inflammatory stimulation in diabetes, hypertension, and PCOS [9][10][11]. It may also affect the control of the reproduction system, e.g. puberty onset and gonadotropin secretion [12]. ABSTRACTObesity, insulin resistance (IR), inflammation, and hyperandrogenism may lead to polycystic ovary syndrome (PCOS) and hypertension. Nesfatin-1 (N1) may be related to IR, obesity, and hypertension. Furthermore, a vitamin D (VD) deficiency is associated with hypertension and PCOS. We aimed to investigate N1 and VD levels in PCOS that have an effect on systolic and diastolic blood pressure (BP) and heart rate (HR). This study included 54 patients with PCOS and 48 age-body mass index (BMI)-matched healthy controls. PCOS was diagnosed according to clinical practice guidelines. Ferriman-Gallwey scores (FGS) were calculated, while N1, VD, and other hormonal and biochemical parameters were measured for all subjects. Systolic and diastolic BP was measured as well. HR was calculated using an electrocardiogram. The levels of N1 (p < 0.001), high-sensitivity C-reactive protein (hs-CRP) (p = 0.036), homeostasis model assessment as an index of insulin resistance (HOMA-IR) (p < 0.001), systolic (p < 0.001) and diastolic (p < 0.001) BP and HR (p < 0.001) in the PCOS group were significantly higher than in the control group. However, the VD levels of the PCOS group were lower than the control group (p = 0.004). N1 had a strong positive correlation with BMI, HOMA-IR, hs-CRP, luteinizing hormone, systolic and diastolic BP, and HR. VD levels were negatively correlated with HOMA-IR and luteinizing hormone. Elevated N1 and decreased VD levels may...

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Section: Inclusion Criteriamentioning

confidence: 99%

Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome

Şahin

Ural

et al. 2015

Biomol Biomed

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“…[22][23][24] Briefly, as part of a larger study, 805 non-Hispanic black, non-Hispanic white, and Hispanic women between 16 and 33 years of age were recruited between October 9, 2001, and September 14, 2004, to examine the effect of hormonal contraceptives on bone mineral density. Women were recruited from those who responded to advertisements and mailed announcements.…”

Section: Methodsmentioning

confidence: 99%

Self-Perception of Weight Gain Among Multiethnic Reproductive-Age Women

Rahman

Berenson²

2012

Journal of Women's Health

Self Cite

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Objective: To examine the accuracy of self-perception of weight gain and its correlates in a multiethnic reproductive-age population of women. Methods: A total of 608 women (balanced by contraceptive methods and race/ethnicity) self-reported their perceptions of weight gain at baseline and every 6 months thereafter for 36 months. Data regarding body weight, height, and other covariates were also obtained. Women with at least two follow-up visits were included in the final analysis. Generalized estimating equations (GEE) models were used to examine correlates of the accuracy of self-perception of weight gain over time. Results: Overall, 466 women had at least two follow-up visits with 1744 total observations over 36 months. In total, 44%, 30%, 19%, 12%, and 8% observations had at least 1, 2, 3, 4, and 5 kg weight gain in 6 months while 59%, 67%, 73%, 78%, and 85% of women accurately recognized it, respectively. Depot medroxyprogesterone (DMPA) users were more likely than nonhormonal method users (69%/51%, 76%/59%, 81%/63%, 85%/59%, and 93%/71%), and blacks more likely than whites (70%/51%, 76%/59%, 83%/65%, 90%/68%, and 95%/78%) ( p < 0.05 for all) to recognize weight gains of 1, 2, 3, 4, and 5 kg. The differences remained significant after adjusting for covariates using GEE. A significant difference was also observed between DMPA and oral contraceptive users. Conclusions: Inability to recognize weight gain is common among young women. Both race/ethnicity and contraceptive methods influence the accurate perception of weight gain. Clinicians should provide patientspecific counseling to address the frequent inaccuracies to recognize weight gain.

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“…A pro forma is made for screening patients of metabolic syndrome and also assessing their demographic profile, history of previous illness and medication, anthropometric measurement including weight and height for calculating body mass index (BMI = weight in Kg/height in m Similarly, hypertension and hyperglycemia were categorized according to standard definition [11,12]. For measuring waist circumference, the distance between anterior superior iliac spines and the lower costal margin at the narrowest part of the waistline was calculated during expiration while putting patient in standing position.…”

Section: Screening Pro Formamentioning

confidence: 99%

Prevalence of Nonalcoholic - Fatty Liver Disease in Metabolic Syndrome - A Hospital-Based Cross-Sectional Study

Kajaria

2017

Asian J Pharm Clin Res

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Objective: 21 st century is dedicated to noncommunicable diseases; it may be diabetes, hypertension, obesity, or constellation of all known as metabolic syndrome. The main objective of this paper is to assess the prevalence of nonalcoholic fatty liver disease (NFLDS) in metabolic syndrome and its impact on the severity of metabolic syndrome in term of dyslipidemia, mean systolic pressure and body mass index (BMI). Methods:A cross-sectional study was conducted on 100 patients selected randomly during the period of January 2017-March 2017 from the outdoor patient department of Kayachikitsa of All India Institute of Ayurveda. Patient included on the basis of a screening pro forma based on the diagnostic criteria of metabolic syndrome on the basis of Third Adult Treatment Panel of the National Cholesterol Education Program criteria and 50 controls were included in the study. Pro forma also included general information regarding previous illness, socioeconomical status, BMI, evaluation of vital parameters, and lipid and thyroid profile, along with other routine laboratory parameters. Ultrasonography report is taken as the evidence for the diagnosis of fatty liver disease.Results: Frequency distributions and Chi-square statistics were used for categorical variables. Logistic regression analyses Students' t-test, Chi-square test, linear regression, and multiple logistic regression models were used for statistical analysis. p<0.05 was considered significant. BMI, waist circumference, mean systolic pressure, diastolic blood pressure, fasting blood sugar, triglycerides, total cholesterol, low-density lipoprotein (LDL) cholesterol were significantly higher, and high-density lipoprotein cholesterol, was significantly low in the study group compared to the control group. In the metabolic syndrome group, 67 patients (67%) had fatty liver Grade I, 34 had Grade II fatty liver (34%), 6 patients were having hepatomegaly with coarse echotexture (6%) and 4 patients were having cholelithiasis. NFLDS was significantly associated with metabolic syndrome group (p<0.0001). There was a significant linear association between fatty infiltration in liver and BMI, total cholesterol, triglycerides, and LDL cholesterol in the metabolic syndrome group in the linear regression model. Multiple logistic regression analysis recognized the association between fatty liver disease and BMI with dyslipidemia (p<0.001) in the metabolic syndrome group. Conclusion:It is concluded from this study that there is a significant association between NFLDS and metabolic syndrome, and it highlights the importance of evaluating liver profile in patients with metabolic syndrome.

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Accuracy of Current Body Mass Index Obesity Classification for White, Black, and Hispanic Reproductive-Age Women

Cited by 148 publications

References 26 publications

Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome

Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome

Self-Perception of Weight Gain Among Multiethnic Reproductive-Age Women

Prevalence of Nonalcoholic - Fatty Liver Disease in Metabolic Syndrome - A Hospital-Based Cross-Sectional Study

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