Accuracy of CT-guided transthoracic needle biopsy of lung lesions: Factors affecting diagnostic yield

Priola, Adriano Massimiliano; Priola, Sandro Massimo; Cataldi, Aldo; Errico, Luca; Franco, Marisa Di; Campisi, Paola; Molinaro, Luca; Marci, Valerio; Novello, Silvia; Fava, Cesare

doi:10.1007/s11547-007-0212-y

Cited by 74 publications

(62 citation statements)

References 38 publications

(37 reference statements)

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“…In those cases, especially where two pleural planes need to be traversed, the transthoracic approach contains a high risk for the development of a pneumothorax [14]. Furthermore, the sensitivity of transthoracic needle aspiration drops with increasing distance between the nodule and the pleura [15]. BTPNA was applied in surgically fit patients only, which depicts a limitation of the study since the results cannot simply be generalized on inoperable patients.…”

Section: Discussionmentioning

confidence: 99%

Bronchoscopic Transparenchymal Nodule Access: Feasibility and Safety in an Endoscopic Unit

Harzheim¹,

Sterman

Shah³

et al. 2016

Respiration

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Background: The minimal invasive investigation of solitary pulmonary nodules becomes increasingly important with the emergence of lung cancer screening. Objectives: We report the results of the first utilization of a recently developed procedure in a bronchoscopy suite, which approaches solitary pulmonary nodules via a transparenchymal path. Methods: This study was a prospective, single-arm interventional study. We investigated patients with a solitary pulmonary nodule detected on CT imaging, which was suspicious for malignancy. The subject's CT was employed to calculate an airway wall point of entry (POE) as well as an avascular path through lung tissue from the POE to the solitary pulmonary nodule. Using a set of catheter-based tools under fused fluoroscopy guidance, a tunnelled tract was created from the POE to the nodule. The patients were surveyed for at least 72 h in our hospital. The primary end point of the study was to evaluate the feasibility to access and biopsy solitary pulmonary nodules outside of an operation theatre. Results: Six patients were recruited, and a tunnel pathway was created in 5 patients. There were no adverse events during the procedures. Two pneumothoraces were diagnosed by chest X-ray 2 h after the procedure, with one pneumothorax requiring drainage. Adequate biopsies were obtained from all 5 patients in whom a tunnel path was created. Conclusions: This study demonstrates that bronchoscopic transparenchymal access of solitary pulmonary nodules is feasible outside an operation theatre.

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Section: Discussionmentioning

confidence: 99%

Bronchoscopic Transparenchymal Nodule Access: Feasibility and Safety in an Endoscopic Unit

Harzheim¹,

Sterman

Shah³

et al. 2016

Respiration

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“…After evaluation of clinical risk factors and of nodule imaging characteristics, biopsy is recommended for lesions with intermediate or high probability of cancer, and transthoracic needle biopsy (TNB) is frequently used to achieve definitive pathological diagnosis [1][2][3]. Generally, TNB is performed in the outpatient setting, with few complications.…”

Section: Introductionmentioning

confidence: 99%

Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules

et al. 2015

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“…Actual adequacy rates vary [20]; we routinely expect diagnostic results from about 95% of lung biopsies performed by interventional radiologists at our institution. Although no formal model has been widely adopted to systematize the concordance or discordance of radiologic appearance and pathologic diagnoses, we believe that review of the biopsy result by the radiologist adds important value.…”

Section: Resultsmentioning

confidence: 99%

The Interventional Radiologist’s Perspective on Lung Biopsy

Elnekave¹,

Thornton²

2012

Acta Cytologica

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Accuracy of CT-guided transthoracic needle biopsy of lung lesions: Factors affecting diagnostic yield

Abstract: In CT-guided transthoracic needle biopsy, the final diagnosis and lesion size affect diagnostic accuracy: benign lung lesions and lesions smaller than 1.5 cm or larger than 5.0 cm in diameter provide lower diagnostic yield.

Cited by 74 publications

References 38 publications

Bronchoscopic Transparenchymal Nodule Access: Feasibility and Safety in an Endoscopic Unit

Bronchoscopic Transparenchymal Nodule Access: Feasibility and Safety in an Endoscopic Unit

Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules

The Interventional Radiologist’s Perspective on Lung Biopsy

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