Accuracy of contrast-enhanced ultrasound (CEUS) in the identification and characterization of traumatic solid organ lesions in children: a retrospective comparison with baseline US and CE-MDCT

Menichini, G; Sessa, Barbara; Trinci, Margherita; Galluzzo, Michele; Miele, Vittorio

doi:10.1007/s11547-015-0535-z

Cited by 94 publications

(61 citation statements)

References 33 publications

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“…29 CEUS is perfectly suited for the follow-up of patients with paediatric trauma, without the need for ionizing radiation, sedation and nephrotoxic contrast agents and no compromise in terms of diagnostic accuracy. 31 A recently published retrospective analysis of 73 haemodynamically stable children sustaining minor abdominal trauma compared CEUS with baseline ultrasonography and CT. 37 In this study, ultrasonography detected only 26/67 (38.8%) parenchymal traumatic lesions involving the liver, spleen and kidneys, whereas CEUS was concordant with CT in every patient ( Figure 1). CEUS also identified active parenchymal bleeding in 50% of cases seen on CT and one case of partial devascularization.…”

Section: Clinical Applications Blunt Abdominal Traumamentioning

confidence: 53%

“…CEUS also identified active parenchymal bleeding in 50% of cases seen on CT and one case of partial devascularization. 37 CEUS has been shown to detail renal cortical necrosis in a child following blunt abdominal trauma. CEUS findings were correlated and confirmed by gadolinium-enhanced MRI, indicating its excellent spatial resolution.…”

Section: Clinical Applications Blunt Abdominal Traumamentioning

confidence: 99%

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Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

Rafailidis¹,

Deganello²,

Watson³

et al. 2017

BJR

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Contrast-enhanced ultrasound (CEUS) represents a complementary technique to greyscale and colour Doppler ultrasonography which allows for real-time visualization and characterization of tissue perfusion. Its inherent advantages in the child makes ultrasonography an ideal imaging modality; repeatability and good tolerance along with the avoidance of CT, a source of ionizing radiation, renders ultrasonography imaging desirable. Although currently paediatric CEUS is principally used in an "off-label" manner, ultrasonography contrast agents have received regulatory approval for assessment of paediatric focal liver lesions (FLL) in the USA. The safety of ultrasound contrast-agents is well documented in adults, as safe as or even surpassing the safety profile of CT and MR contrast agents. Except for the established intracavitary use of CEUS in voiding urosonography, i.v. paediatric applications have been introduced with promising results in the abdominal trauma initial diagnosis and follow-up, characterization and differential diagnosis of FLL and characterization of lung, pleura, renal and splenic pathology. CEUS has also been used to detect complications after paediatric transplantation, evaluate inflammatory bowel disease activity and assess tumour response to antiangiogenic therapy. The purpose of this review was to present these novel i.v. paediatric applications of CEUS and discuss their value.

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Section: Clinical Applications Blunt Abdominal Traumamentioning

confidence: 53%

Section: Clinical Applications Blunt Abdominal Traumamentioning

confidence: 99%

Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

Rafailidis¹,

Deganello²,

Watson³

et al. 2017

BJR

View full text Add to dashboard Cite

show abstract

“…However, in many experiences, CEUS showed some limits because, besides being operator-dependent, it has a low panoramicity and does not provide important information about possible complications, such as the presence of bilomas, abscesses, urinary tract, and vascular lesions [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

“…However CEUS has shown some limits, such as the fact that it is operator-dependent, has a low panoramicity, the small operating window reducing the visibility, and its low capability to give useful information about some complications, such as abscesses, bilomas, lesions to the urinary tract and vascular complications, requiring the use of CE-CT [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Comparison between MRI and CEUS in the follow-up of patients with blunt abdominal trauma managed conservatively

et al. 2015

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MRI allowed to make a better assessment of injuries than CEUS, allowing also a temporal stage of lesions. Infact, there are different evolution stages corresponding to accurate imaging findings. To our knowledge, this is the first study that describes the evolution of blood collection in parenchymal abdominal organs. Therefore, in patients who underwent abdominal traumatic injuries conservatively treated, the follow-up at 1 month can be made by MRI, due to its panoramicity and its high contrast resolution, which allow a better morphological and temporal trauma staging respect to the CEUS.

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“…In trauma, CEUS has shown to be a reliable tool in the diagnosis and follow-up of liver, spleen and renal injuries in pediatric patients [147,148].…”

Section: Pediatric Populationmentioning

confidence: 99%

Romanian National Guidelines on Contrast Enhanced Ultrasound in clinical practice

et al. 2017

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Contrast-enhanced ultrasound (CEUS) allows a real-time assessment of the vascular pattern of different types of lesions, as it has no renal or liver toxicity, it lacks radiation exposure and it is also cheaper than other imaging methods, having a diagnostic capability that matches contrast-enhanced CT or MRI. In Romania CEUS is used more and more, especially by clinicians, and since some centres have extensive experience in this domain, we felt the need to disseminate our expertise in order to implement this method in as many centres as possible. These Guidelines present the clinical applications of CEUS in the liver, spleen, pancreas, kidney, testis, bowel, intra-cavitary and endoscopic ultrasound, as well as other applications.

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Accuracy of contrast-enhanced ultrasound (CEUS) in the identification and characterization of traumatic solid organ lesions in children: a retrospective comparison with baseline US and CE-MDCT

Cited by 94 publications

References 33 publications

Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

Comparison between MRI and CEUS in the follow-up of patients with blunt abdominal trauma managed conservatively

Romanian National Guidelines on Contrast Enhanced Ultrasound in clinical practice

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