Accuracy of continuous glucose monitoring system during exercise in type 2 diabetes

Figueira, Franciele Ramos; Umpierre, Daniel; Ribeiro, Jorge Pinto; Tetelbom, Pedro S.; Henn, Nicoli Taiana; Esteves, J; Schaan, Beatriz D.

doi:10.1016/j.diabres.2012.09.033

Cited by 10 publications

(8 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The concordance of CGMS and self monitoring of blood glucose (SMBG) was recently assessed in patients with type 2 diabetes, during daily activities and two different exercise sessions [11]. Agreement between SMBG and CGMS was lower during exercise, but more than 90% of the readings were similar.…”

Section: Continuous Glucose Monitoring Systemmentioning

confidence: 99%

“…Five studies focused on the risk for hypoglycaemia [11][12][13]17,31], after different types of exercise. Praet et al [21] and Van Dijk et al [29] did not find changes in the duration or the number of episodes of hypoglycaemia, respectively, during the 24-h time frame following exercise.…”

Section: Differences In the Acute Effect Of Exercise On Glucose Contrmentioning

confidence: 99%

“…However, both these approaches greatly limit the possibility of monitoring blood glucose changes over prolonged periods in real life conditions. In the last few years, a new tool, the continuous glucose monitoring system (CGMS), has been validated and is increasingly used in clinical practice, as it allows physicians and researchers to continuously monitor glucose levels in real life conditions, including physical activity, for several consecutive days [11,12]. In this article we review the literature regarding the acute effect of exercise on glucose control in subjects with type 2 diabetes, as measured by CGMS.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of Acute Bouts of Exercise on Blood Glucose in Type 2 Diabetic Patients, as Measured by Continuous Glucose Monitoring Systems

Negri¹

2013

J Diabetes Metab

View full text Add to dashboard Cite

Literature data indicate that the effect on blood glucose levels of a single bout of exercise may persist up to 48-h after cessation of exercise. Regular exercise improves insulin sensitivity and blood glucose control in subjects with type 2 diabetes and is considered a key element in the management of this condition. However, adaptive responses to exercise are altered in diabetic subjects and medications used in these patients may cause inappropriate insulin levels for the concurrent blood glucose concentrations, with a possible increase in risk for hypoglycaemia. Recently, the development and clinical availability of systems for the continuous monitoring of glucose (continuous glucose monitoring system, CGMS), have made it possible to continuously record blood glucose levels for several days in real life conditions, showing that possible differences in blood glucose levels of these individuals may occur during and after a single bout of exercise, depending on the characteristics of the physical activity. In particular, differences between aerobic vs resistance exercise and between low-intensity vs high-intensity exercise have been reported. However, there are only a few, small heterogeneous studies on this topic, and results are to some extent discordant, limiting any conclusions. Further research on this issue is needed before we can reach clear conclusions. In particular, the role of differences in frequency, duration, intensity, type and timing of exercise needs to be carefully investigated. Hopefully, this information will assist clinicians and exercise specialists in designing personalized exercise programmes and strategies aimed at optimally improving glucose control of type 2 diabetic patients, also limiting the risk for hypoglycaemia. In this article, we review the literature regarding the acute effect of different types of exercise on glucose levels, as measured by CGMS, in subjects with type 2 diabetes. J ou rna l o f D ia be tes & M e ta bolism

show abstract

Section: Continuous Glucose Monitoring Systemmentioning

confidence: 99%

Section: Differences In the Acute Effect Of Exercise On Glucose Contrmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of Acute Bouts of Exercise on Blood Glucose in Type 2 Diabetic Patients, as Measured by Continuous Glucose Monitoring Systems

Negri¹

2013

J Diabetes Metab

View full text Add to dashboard Cite

show abstract

“…Exercise rapidly alters venous glucose concentrations in patients with type 2 diabetes, particularly exercise performed in the postprandial period (14,19,20). In both nondiabetic and diabetic patients, subcutaneous adipose tissue interstitial glucose concentrations (measured with a continuous glucose monitor) were shown to be higher compared with capillary or venous glucose concentrations during aerobic and/or resistance exercise (11,15,18,22). In another study, the mean difference between subcutaneous adipose tissue interstitial and venous glucose concentrations was greater during low-intensity exercise, whereas the mean difference was lower during highintensity exercise in patients with type 1 diabetes (10).…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, this study sought to determine how distinct phases of the postprandial glucose profile compares between the interstitial and venous compartments. Given that prior research (11,15,18,22) has shown that interstitial glucose concentrations during the fasted state are higher during exercise compared with venous glucose concentrations, we hypothesized that subcutaneous interstitial glucose concentrations during postprandial resistance exercise would be higher compared with venous blood glucose concentrations in individuals with type 2 diabetes.…”

Section: Introductionmentioning

confidence: 99%

A comparison of adipose tissue interstitial glucose and venous blood glucose during postprandial resistance exercise in patients with type 2 diabetes

Heden

Liu

Kanaley

2018

Journal of Applied Physiology

View full text Add to dashboard Cite

Resistance exercise during the postprandial period lowers venous glucose concentrations in individuals with type 2 diabetes, but the impact of resistance exercise on interstitial glucose concentrations is not well understood. The objective of this study was to compare subcutaneous adipose tissue interstitial glucose and venous blood glucose concentrations during postprandial resistance exercise in patients with type 2 diabetes. Eleven individuals completed two trials in a random order including a no-exercise (NoEx) and a postprandial resistance exercise trial (M-Ex). During the trials, the individuals consumed a meal and either remained sedentary (NoEx) or performed a session of resistance training beginning 45 min after the meal (M-Ex) while interstitial and venous glucose concentrations were simultaneously measured. Venous glucose during exercise was ~11% lower ( P = 0.05) during M-Ex (8.0 ± 0.5 mmol/l) compared with NoEx (9.0 ± 0.5 mmol/l) whereas interstitial glucose during M-Ex (10.4 ± 0.7 mmol/l) was not different compared with interstitial glucose during NoEx (10.1 ± 0.7 mmol/l). Bland-Altman plots revealed that the difference (bias) between interstitial and venous glucose during exercise was more than twofold greater during M-Ex (2.36 ± 2.07 mmol/l) compared with NoEx (1.11 ± 1.69 mmol/l). The mean (33.8 ± 6.2 mmol/l) and median (34.7 ± 6.3 mmol/l) absolute relative difference during exercise were 73% and 78% greater compared with the mean (19.5 ± 4.1 mmol/l) and median (19.5 ± 4.1 mmol/l) absolute relative difference during NoEx ( P = 0.04). Resistance exercise has unequal effects on glucose concentrations within different bodily compartments as exercise reduced venous glucose concentrations but not adipose tissue interstitial glucose concentrations in the abdominal region in individuals with type 2 diabetes. NEW & NOTEWORTHY This is the first study to compare subcutaneous adipose tissue interstitial glucose concentrations and venous blood glucose concentrations during postprandial resistance exercise in individuals with type 2 diabetes. We find that resistance exercise effectively reduces systemic venous blood glucose concentrations but not subcutaneous adipose tissue interstitial glucose concentrations in the abdominal region. Resistance exercise has differential effects on glucose concentrations depending on its compartmentalization within the body.

show abstract

Exercise for Athletes with Diabetes

Ohri

Schneider

Wilson³

et al. 2015

Nutritional Supplements in Sports and Exercise

View full text Add to dashboard Cite

Physical activity has long been considered to be benefi cial to individuals with all forms of diabetes mellitus. Regular exercise improves glucose control and a variety of metabolic risk factors associated with the disease. In addition, exercise may decrease the risk for developing diabetes in individuals at risk. Most of the benefi ts of physical activity are related to improved insulin sensitivity and glucose uptake resulting in changes in body weight and composition. Athletes with diabetes mellitus need education and guidance regarding concerns with athletic activity in patients with diabetes including hypoglycemia and hyperglycemia in an attempt to maintain their overall health status. In addition the effects of exercise are often altered by many of the medications in common use in this population. With appropriate prescreening for relevant complications and proper understanding of diet and drug interactions, most athletes with diabetes mellitus can enjoy the benefi ts of physical activity safely. Keywords

show abstract

Accuracy of continuous glucose monitoring system during exercise in type 2 diabetes

Cited by 10 publications

References 12 publications

Influence of Acute Bouts of Exercise on Blood Glucose in Type 2 Diabetic Patients, as Measured by Continuous Glucose Monitoring Systems

Influence of Acute Bouts of Exercise on Blood Glucose in Type 2 Diabetic Patients, as Measured by Continuous Glucose Monitoring Systems

A comparison of adipose tissue interstitial glucose and venous blood glucose during postprandial resistance exercise in patients with type 2 diabetes

Exercise for Athletes with Diabetes

Contact Info

Product

Resources

About