Accuracy of 18-F-FDG PET imaging in the follow up of endometrial cancer patients: Systematic review and meta-analysis of the literature

Diagnostic Performance of Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography Imaging for Detection of Primary Lesion and Staging of Endometrial Cancer Patients: Systematic Review and Meta-Analysis of the Literature

“…5Y7 For endometrial cancer, 18 F-FDG PET imaging has been used for staging and detection of recurrence with different results. 8,9 In the current study, we systematically searched the available literature on the accuracy of 18 F-FDG PET imaging for staging of endometrial cancer and presented the results in metaanalytic format.…”

Treatment Failure in Endometrial Carcinoma

“…A recently published meta-analysis estimated a treatment plan change rate of 22% to 35% by PET or PET/CT. 23 In this series, most of the treatment plans were based on the PET or PET/CT findings, which achieved a 5-year SAR of 56.6% in patients with extravaginal recurrences treated with surgery T RT T chemotherapy and a 5-year SAR of 83.3% in patients with isolated vaginal recurrence and received RT alone.…”

PET/MRI Evaluation of Gynecologic Malignancies and Prostate Cancer

“…35 A recent review and meta-analysis of the published literature showed that FDG-PET has a sensitivity of 95.8% (95%CI: 92.2%-98.1%), specificity of 92.5% (89.3%-94.9%), positive likelihood ratio of 9.53 (6.52-13.91), negative likelihood ratio of 0.075 (0.044-0.128), and diagnostic odds ratio of 204 (91.97-453.5) for detection of overall disease recurrence on patient-based analysis with better performance by PET/CT as compared with PET. 37 PET resulted in change of the treatment plan in 22%-35% of the patients. Although currently there are no studies using hybrid PET/MR scanners for evaluation of recurrent endometrial cancer, considering the advantages of this hybrid modality, it is expected that the combined PET/ MRI will be very useful in posttherapy evaluation of patients with endometrial cancer.…”