Objective
Clinical examination of the knee is subject to measurement error. The
aim of this analysis was to determine inter- and intra-observer reliability
of commonly used clinical tests in patients with knee
osteoarthritis(OA).
Methods
We studied subjects with symptomatic knee OA who were participants in
an open-label clinical trial of intra-articular steroid therapy. Following
standardisation of the clinical test procedures, two clinicians assessed 25
subjects independently at the same visit, and the same clinician assessed 88
subjects over an interval period of 2–10 weeks; in both cases prior
to the steroid intervention. Clinical examination included assessment of
bony enlargement, crepitus, quadriceps wasting, knee effusion, joint-line
and anserine tenderness and knee range of movement(ROM). Intra-class
correlation coefficients(ICC), estimated kappa(К), weighted
kappa(Кω) and Bland and Altman plots were used
to determine inter- and intra-observer levels of agreement.
Results
Using Landis and Koch criteria, inter-observer kappa scores were
moderate for patellofemoral joint(К=0.53) and anserine
tenderness(К=0.48); good for bony enlargement(К=0.66),
quadriceps wasting(К=0.78), crepitus(К=0.78), medial
tibiofemoral joint tenderness(К=0.76), and effusion assessed by
ballottement(К=0.73) and bulge
sign(Кω=0.78); and excellent for lateral
tibiofemoral joint tenderness(К=1.00), flexion(ICC=0.97) and
extension(ICC=0.87) ROM. Intra-observer kappa scores were moderate for
lateral tibiofemoral joint tenderness(К=0.60), good for
crepitus(К=0.78), effusion assessed by ballottement
test(К=0.77), patellofemoral joint(К=0.66), medial
tibiofemoral joint(К=0.64) and anserine(К=0.73) tenderness and
excellent for effusion assessed by bulge
sign(Кω=0.83), bony enlargement(К=0.98),
quadriceps wasting(К=0.83), flexion(ICC=0.99) and extension(ICC=0.96)
ROM.
Conclusion
Among individuals with symptomatic knee OA, the reliability of
clinical examination of the knee was at least good for the majority of
clinical signs of knee OA.