Accumulation of99mTc-PMT in renal metastasis of hepatocellular carcinoma

Shiozaki, Toshiki; Hayakawa, Katsumi; Tanikake, Masato; Oida, Tomoyuki; Hida, S; Urata, Yoji; Morimoto, Tetsuya

doi:10.1007/bf02988531

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…However, lipid-poor adenoma cannot be diagnosed by this procedure and both adenoma and metastatic HCC often show similar findings of early enhancement and washout. 99 Tc m pyridoxyl-5-methyl tryptophan hepatobiliary scintigraphy is useful for specifically diagnosing metastatic HCC but only when the tumour cells produce bile [15][16][17]. We estimate that the uptake of Gd-EOB-DTPA in any masses outside the liver is also a specific finding of metastatic lesions from HCC and that this finding is useful for diagnosing metastatic tumours from HCC, although its sensitivity is presumably low.…”

Section: Discussionmentioning

confidence: 90%

Uptake of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid in metastatic adrenal tumour from hepatocellular carcinoma

Arizono

Isoda²,

Hatano³

et al. 2011

BJR

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Section: Discussionmentioning

confidence: 90%

Uptake of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid in metastatic adrenal tumour from hepatocellular carcinoma

Arizono

Isoda²,

Hatano³

et al. 2011

BJR

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“…Primary tumors of the lungs, breasts, and gastrointestinal tract are the most common origins of renal metastasis; renal metastases from HCC are exceedingly rare. In a literature search using PubMed, we identified only six cases of renal metastasis from HCC [ 25 – 30 ]. Tumor markers such as α-fetoprotein and imaging findings may be helpful for diagnosis in these cases; tumor rupture was also observed in some cases.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous gastric, pancreatic, and renal metastasis from poorly differentiated hepatocellular carcinoma

Uchikoshi,

Ito,

Nakajima

et al. 2024

Clin J Gastroenterol

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Common extrahepatic metastasis sites of hepatocellular carcinoma (HCC) are the lungs, adrenal glands, and bones. Herein, we report a rare case of metastatic gastric, pancreatic, and renal tumors from HCC simultaneously, and review the relevant literature. A 75-year-old woman presented with right hypochondralgia, appetite loss, and weight loss. Computed tomography revealed suspected metastatic liver, lung, and renal tumors. A blood test revealed a leukocyte count of 26,210/μL and a high inflammatory reaction. As sepsis was suspected, the patient was referred to our hospital. Gadolinium–ethoxybenzyl–diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging revealed a hypovascular liver tumor that was suspected to be metastatic. Upper gastrointestinal endoscopy revealed two suspected metastatic gastric tumors. Liver and gastric tumor biopsies revealed poor carcinoma in both. The patient’s condition gradually worsened and she died on day 8 of the illness. Based on autopsy findings, the patient was finally diagnosed with metastatic gastric and renal tumors originating from HCC. Additionally, a metastatic pancreatic tumor originating from the HCC was identified during autopsy. The pathological diagnosis of the pulmonary lesion was primary lung adenocarcinoma. In conclusion, HCC should be suspected in cases with multiple metastases of unknown primary lesions.

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“…There are a few case reports [27][28][29]. Isolated kidney metastasis may be treated with nephrectomy but the prognosis is very poor.…”

Section: Hepatitis B Virus Infection Is a Very Important Health Issuementioning

confidence: 99%

A case of recurrent metastatic hepatocellular cancer controlled with immunotherapy and antiviral therapy following resection

et al. 2009

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Hepatocellular carcinoma (HCC) is the most frequent malignant tumour of the liver. The risk of HCC in chronically hepatitis B virus (HBV) infected individuals is approximately 100-fold higher than in the uninfected population. Despite all therapeutic advances, the benefit of systemic chemotherapy in patients with HCC has limited. But, the phase III clinical trial conducted in patients with advanced HCC treated with sorafenib has showed significant improvements in both overall and progression-free survival Metastasis from liver to extrahepatic tissues is reported to be quite uncommon and has a poor prognosis. Here we present a case of HCC which metastasized to the vertebrae, lung and kidney in order of appearance and controlled with immunotherapy and antiviral therapy following resection.

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Accumulation of99mTc-PMT in renal metastasis of hepatocellular carcinoma

Cited by 3 publications

References 7 publications

Uptake of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid in metastatic adrenal tumour from hepatocellular carcinoma

Uptake of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid in metastatic adrenal tumour from hepatocellular carcinoma

Simultaneous gastric, pancreatic, and renal metastasis from poorly differentiated hepatocellular carcinoma

A case of recurrent metastatic hepatocellular cancer controlled with immunotherapy and antiviral therapy following resection

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