Accumulation of Moderate‐to‐Vigorous Physical Activity and All‐Cause Mortality

Young, Deborah Rohm; Haskell, William L.

doi:10.1161/jaha.118.008929

Cited by 7 publications

(5 citation statements)

References 11 publications

(19 reference statements)

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“…MVPA in 10‐minute bouts is considered more intentional movement and synonymous with planned and structured physical activity. Recent evidence suggests health benefits are associated with MVPA regardless of how MVPA is accumulated, 27,28 however, our models suggested expected QOL and fatigue improvements doubled when MVPA in 10‐minute bouts increased by 1 hour per day. For physical health, the most substantial benefit was found for participants in the lowest percentile of physical health scores.…”

Section: Discussioncontrasting

confidence: 63%

Associations of device‐measured physical activity and sedentary time with quality of life and fatigue in newly diagnosed breast cancer patients: Baseline results from the AMBER cohort study

Vallance

Friedenreich

Wang

et al. 2022

Cancer

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Background This study examined associations of device‐measured physical activity and sedentary time with quality of life (QOL) and fatigue in newly diagnosed breast cancer patients in the Alberta Moving Beyond Breast Cancer (AMBER) cohort study. Methods After diagnosis, 1409 participants completed the SF‐36 version 2 and the Fatigue Scale, wore an ActiGraph device on their right hip to measure physical activity, and an activPAL device on their thigh to measure sedentary time (sitting/lying) and steps. ActiGraph data was analyzed using a hybrid machine learning method (R Sojourn package, Soj3x) and activPAL data were analyzed using activPAL algorithms (PAL Software version 8). Quantile regression was used to examine cross‐sectional associations of QOL and fatigue with steps, physical activity, and sedentary hours at the 25th, 50th, and 75th percentiles of the QOL and fatigue distributions. Results Total daily moderate and vigorous physical activity (MVPA) hours was positively associated with better physical QOL at the 25th (β = 2.14, p = <.001), 50th (β = 1.98, p = <.001), and 75th percentiles (β = 1.25, p = .003); better mental QOL at the 25th (β = 1.73, p = .05) and 50th percentiles (β = 1.07, p = .03); and less fatigue at the 25th (β = 4.44, p < .001), 50th (β = 3.08, p = <.001), and 75th percentiles (β = 1.51, p = <.001). Similar patterns of associations were observed for daily steps. Total sedentary hours was associated with worse fatigue at the 25th (β = −0.58, p = .05), 50th (β = −0.39, p = .06), and 75th percentiles (β = −0.24, p = .02). Sedentary hours were not associated with physical or mental QOL. Conclusions MVPA and steps were associated with better physical and mental QOL and less fatigue in newly diagnosed breast cancer patients. Higher sedentary time was associated with greater fatigue symptoms.

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Section: Discussioncontrasting

confidence: 63%

Associations of device‐measured physical activity and sedentary time with quality of life and fatigue in newly diagnosed breast cancer patients: Baseline results from the AMBER cohort study

Vallance

Friedenreich

Wang

et al. 2022

Cancer

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“…The health benefits of moderate-to-vigorous physical activity (MVPA) have been advocated for decades. Virtually all epidemiological studies have prompted advocating that people increase MVPA as an important part of preventing disease and premature mortality [ 1 , 2 , 3 , 4 , 5 ]. The effects of different types of MVPA-related exposure indicators and activity patterns are required to provide targets for physical activity (PA) intervention [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Trajectories of 24-Hour Physical Activity Distribution and Relationship with Dyslipidemia

Wang

et al. 2023

Nutrients

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The association between physical activity (PA) and dyslipidemia is well known, but the relationship between a temporal pattern of PA and dyslipidemia remain unknown. Here, we aimed to identify the intensity and temporal patterns of PA clustered by the trajectory model and their relationship with dyslipidemia. The participants were 701 adults (305 males) aged 18–60 years undergoing continuous measurement of PA with Actigraph GT3X+ accelerometers for at least 3 days. A trajectory analysis was applied based on moderate-to-vigorous intensity physical activity (MVPA) accumulated values over every period per day. The association between PA and dyslipidemia was estimated using a logistic regression model. Four distinct PA trajectory groups in the population were identified (continued low, stable and moderate, late increasing, and early increasing). Specifically, the “moderate and stable group” was associated with a decreased rate of high TG (p < 0.05) and the “moderate and stable group” and “late increasing group” were associated with decreased rates of low HDL-C (p < 0.05). In conclusion, there were four activity trajectory groups in this population and the continued low PA trajectory was associated with a high prevalent rate of an abnormal lipid profile, and continued and moderate activity or late afternoon increasing activity might have lower HDL-C distribution.

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“…Even though the normalization of metabolic disorders might not have been the ultimate purpose of physical activity interventions to improve body fitness, several experimental and observational studies have shown that the improvement in fitness or increased PA helped to regulate the biomarkers of MetS to a healthier level [ 11 , 12 , 13 , 14 ]. In particular, a large number of research has focused on moderate-and-above-intensity PA to assess how an individual’s activity level might control the risk factors [ 15 , 16 , 17 ]. For example, the WHO 2020 guideline recommended at least 150 min/week of moderate-to-vigorous physical activity (MVPA) for health benefits [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Sex and Age Differences in Association between Physical Activity and Metabolic Syndrome: Results from NHANES 2003–2006

Lynn

Zipunnikov

2023

Healthcare

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Objective: To examine whether and how sex and age modify the association between accelerometer-based physical activity (PA) and metabolic syndrome (MetS) among American (US) adults. Method: Adults aged ≥20 years old who participated in the mobile center examination during 2003–2006 in the National Health and Nutrition Examination Survey were included for analysis. The total minutes per day of moderate-to-vigorous PA (MVPA) was estimated using ActiGraph. Multivariable logistic regression was used to estimate the odds ratio (OR) of having MetS at an increasing MVPA time. The modification effects of gender and age on the association between MetS and MVPA time were examined by testing for two-way and three-way interaction terms of MVPA time, sex, and age in the model after adjusting for relevant covariates. Results: The prevalence of MetS generally decreased with the MVPA time and was lower in females than in males, although the sex difference varied across age groups. After adjusting for demographic and lifestyle covariates, there was a significant sex difference in how an increased MVPA time lowered the odds of MetS. This interactive effect also varied with age. MVPA benefitted young and middle-age populations up until about 65 years old for both sexes, and the protective effect weakened with age. Although the effect of MVPA was stronger for males than females at young ages, the rate at which it attenuated was quicker in males. The OR of MetS between males and females per unit change of MVPA time was 0.73 (95% CI: [0.57, 0.93]) at age = 25 years, compared to OR = 1.00 (95% CI: [0.88, 1.16]) at age = 60 years. Before the age of 50, the gender difference in the protective effect on MetS was larger at low MVPA levels and became smaller at higher MVPA levels. The male advantage was quite stable with an increasing MVPA time for ages 50–60, and no longer significant at older ages. Conclusions: Young and middle-age populations benefitted from MVPA, lowering the risk of MetS for both sexes. A longer MVPA time was associated with a greater decrease in the risk of MetS in young men than in women, but the sex difference reduced with age and was no longer apparent in older populations.

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Accumulation of Moderate‐to‐Vigorous Physical Activity and All‐Cause Mortality

Cited by 7 publications

References 11 publications

Associations of device‐measured physical activity and sedentary time with quality of life and fatigue in newly diagnosed breast cancer patients: Baseline results from the AMBER cohort study

Associations of device‐measured physical activity and sedentary time with quality of life and fatigue in newly diagnosed breast cancer patients: Baseline results from the AMBER cohort study

Trajectories of 24-Hour Physical Activity Distribution and Relationship with Dyslipidemia

Sex and Age Differences in Association between Physical Activity and Metabolic Syndrome: Results from NHANES 2003–2006

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