Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors

Lance, Emilie; Desprat, Julia L.; Holbech, Bente Frost; Gérard, Claudia; Bormans, Myriam; Lawton, Linda A.; Edwards, Christine; Wiegand, Claudia

doi:10.1016/j.aquatox.2016.05.024

Cited by 13 publications

(3 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Eutrophication and associated cyanobacterial harmful algal blooms (CyanoHABs) in surface waters worldwide have been aggravated by increasing nutrient inputs and global warming (Ferguson et al, 1999). CyanoHABs usually produce secondary metabolites, including microcystins (MCs), which have adverse effects on aquatic ecosystems (Rastogi et al, 2014;Lance et al, 2016;Wang et al, 2017). MCs can accumulate in organisms and thus threaten terrestrial animals and humans via food chains or food webs (Machado et al, 2017;Pham and Utsumi, 2018).…”

Section: Introductionmentioning

confidence: 99%

Synergistic toxicity of microcystin-LR and Cu to zebrafish (Danio rerio)

Wei

Shao

et al. 2020

Science of The Total Environment

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Synergistic toxicity of microcystin-LR and Cu to zebrafish (Danio rerio)

Wei

Shao

et al. 2020

Science of The Total Environment

View full text Add to dashboard Cite

“…Comumente são aplicados, ainda, ensaios ecotoxicológicos com o peixe zebrafish (Danio rerio), ou paulistinha, em estudos sobre mecanismos de intoxicação hepática, teratotogenese, reprodução, embriogenese e ciclo de vida (QI et al, 2016;HOU et al, 2016;LI et al, 2015;QIAO et al, 2013;PAVAGADHI et al, 2012). Além disso, trabalhos envolvendo gastrópodes e moluscos (mexilhões comestíveis) em ensaios ecotoxicológicos também podem ser encontrados na literatura (LANCE et al, 2016;FREITAS et al, 2016).…”

Section: Ensaios Ecotoxicológicos Com Cianotoxinasunclassified

CIANOBACTÉRIAS E CIANOTOXINAS EM AMBIENTES AQUÁTICOS: uma breve revisão sobre os principais métodos detecção, remoção e impactos sobre a saúde humana = CYANBACTERIA AND CYANOTOXINS IN AQUATIC ENVIRONMENTS: a short review on the main methods of detection, removal and impacts on human health

Rodrigues

De-Carli

Vicentin

et al. 2021

Bol. Lab. Hidrobiol.

View full text Add to dashboard Cite

Muitos corpos hídricos têm sido degradados devido à interferência humana. A poluição causada pelas atividades antrópicas vem comprometendo a qualidade da água e promovendo eventos de eutrofização, afetando toda estrutura trófica do ambiente, podendo assim acarretar na proliferação de cianobactérias tóxicas. Nesse sentido, o conhecimento sobre esses organismos é de grande importância, principalmente em corpos hídricos com usos múltiplos. Esta pesquisa representa uma revisão de trabalhos publicados envolvendo qualidade ambiental e ecolotoxicologia aquática, tendo como foco estudos relacionados às cianobactérias e cianotoxinas. Para o trabalho foram analisados livros textos e artigos publicados entre 2010 e 2020 em periódicos nacionais e internacionais. Na literatura publicada nos últimos anos são apresentadas as principais metodologias envolvidas na detecção e remoção de cianotoxinas, além de bioensaios ecotoxicológicos. Fica evidente a importância do tratamento de efluentes e controle das fontes de poluição difusas e pontuais no ecossistema promovendo a melhoria da qualidade da água e controle de cianobactérias.ABSTRACTCyanobacteria play an important role among producers in aquatic ecosystems, however when associated with eutrophication they become an ecological and public health problem. The problem involving cyanobacteria is the blooming of potentially toxic strains. The present work aims to present and discuss the problems related to the proliferation of cyanobacteria in limnological environments, and its consequences for dynamics in the environment and effects on environmental health. In this sense, knowledge about these organisms is of great importance, especially in water bodies with multiple uses. This research represents a review of published works involving environmental quality and aquatic ecotoxicology, focusing on studies related to cyanobacteria and cyanotoxins. For the present work, textbooks and articles published between 2010 and 2020 in national and internationaljournals were analyzed. In the literature published in recent years, the main methodologies involved in the detection and removal of cyanotoxins are presented, in addition to ecotoxicological bioassays. The study of cyanobacteria and their metabolites comprises an area of interest that reaches a greater dimension when impacts on the quality of water supply are evident, thus the importance of treating effluents and controlling pollution sources in the ecosystem is evident, promoting improvement and maintenance the quality of the water bodies.

show abstract

“…However, most of the existing studies on the effects of bloom-forming cyanobacteria and/or cyanotoxins on aquatic animals have focused on fish [ 6 ], shellfish [ 7 ], and crustaceans [ 8 ], whereas studies on freshwater gastropods are relatively insufficient. To date, a few reports on the response of freshwater snails to MCs have also been investigated from only a single perspective of bioaccumulation [ 9 ], biochemistry [ 10 ], histopathology [ 11 ], transcriptomics [ 12 ] and metabolomics [ 13 ]. For instance, the toxins in various organs and tissues of Radix swinhoei exposed to microcystin-leucine arginine (MC-LR) showed different distributions [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Integration of Transcriptomics and Microbiomics Reveals the Responses of Bellamya aeruginosa to Toxic Cyanobacteria

Yang

Zhu

et al. 2023

Toxins

View full text Add to dashboard Cite

Frequent outbreaks of harmful cyanobacterial blooms and the cyanotoxins they produce not only seriously jeopardize the health of freshwater ecosystems but also directly affect the survival of aquatic organisms. In this study, the dynamic characteristics and response patterns of transcriptomes and gut microbiomes in gastropod Bellamya aeruginosa were investigated to explore the underlying response mechanisms to toxic cyanobacterial exposure. The results showed that toxic cyanobacteria exposure induced overall hepatopancreatic transcriptome changes. A total of 2128 differentially expressed genes were identified at different exposure stages, which were mainly related to antioxidation, immunity, and metabolism of energy substances. In the early phase (the first 7 days of exposure), the immune system may notably be the primary means of resistance to toxin stress, and it performs apoptosis to kill damaged cells. In the later phase (the last 7 days of exposure), oxidative stress and the degradation activities of exogenous substances play a dominant role, and nutrient substance metabolism provides energy to the body throughout the process. Microbiomic analysis showed that toxic cyanobacteria increased the diversity of gut microbiota, enhanced interactions between gut microbiota, and altered microbiota function. In addition, the changes in gut microbiota were correlated with the expression levels of antioxidant-, immune-, metabolic-related differentially expressed genes. These results provide a comprehensive understanding of gastropods and intestinal microbiota response to toxic cyanobacterial stress.

show abstract

Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors

Cited by 13 publications

References 68 publications

Synergistic toxicity of microcystin-LR and Cu to zebrafish (Danio rerio)

Synergistic toxicity of microcystin-LR and Cu to zebrafish (Danio rerio)

CIANOBACTÉRIAS E CIANOTOXINAS EM AMBIENTES AQUÁTICOS: uma breve revisão sobre os principais métodos detecção, remoção e impactos sobre a saúde humana = CYANBACTERIA AND CYANOTOXINS IN AQUATIC ENVIRONMENTS: a short review on the main methods of detection, removal and impacts on human health

Integration of Transcriptomics and Microbiomics Reveals the Responses of Bellamya aeruginosa to Toxic Cyanobacteria

Contact Info

Product

Resources

About