Accordion Wrinkle Treatment Through the Targeted Use of Botulinum Toxin Injections

Môle, B

doi:10.1007/s00266-013-0134-0

Cited by 9 publications

(16 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Repeated contractions of the OOc and Zmj alongside the connecting fibers can therefore cause lower the crow’s feet and lateral cheek rhytides, forming accordion wrinkles. Accordion wrinkles form from the simultaneous action of two main muscles: the OOc and Zmj acting proximally and distally, respectively [ 12 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

Anatomical contribution of the orbicularis oculi to the zygomaticus major: An improved understanding of the smile with consideration for facial cosmetic procedures

et al. 2022

View full text Add to dashboard Cite

The aim of the present study was to determine the contribution of the orbicularis oculi (OOc) to the zygomaticus major (Zmj) in connecting the orbital region to the corner of the mouth. The OOc and Zmj of 22 embalmed adult Korean cadavers were dissected in 44 hemifaces. The OOc fibers were traced to determine their contribution to the Zmj. Parts of the superficial bundle in the orbital region of the OOc extended directly or indirectly to the Zmj in 22.7% of the specimens. The anatomical contribution of the OOc to the Zmj was divided into three categories depending on whether the connection between them was direct or indirect: (1) superficial orbital OOc fibers extended directly to the Zmj in 6.8% of the specimens, (2) superficial orbital OOc fibers extended to the zygomaticus minor and their small portion joined to the upper fibers of the Zmj in 15.9% of the specimens, and (3) no connection was identified between the OOc and Zmj in 77.3% of the specimens. The results of this study provide further anatomical insight into the relationship between the OOc and zygomaticus muscle complex. This information could be helpful for elucidating the anatomy of smiling and treatment and surgery designs for balanced or ideal smiles.

show abstract

Section: Discussionmentioning

confidence: 99%

Anatomical contribution of the orbicularis oculi to the zygomaticus major: An improved understanding of the smile with consideration for facial cosmetic procedures

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Patients who have experienced substantial photoaging and loss of volume may develop sets of fine parallel lines, which may also be deep, stretching from the orbital frame up to the temples and neck—a condition variously described as “scratched face” or “accordion lines.” 50,51 Hypertrophy of the orbicularis and the zygomaticus major are responsible for periorbital and para-commissural wrinkles, but wrinkles may also appear at some distance from these muscles.…”

Section: Aesthetic Developmentsmentioning

confidence: 99%

“…The effects may be explained by diffusion of toxin into dermal cells (facilitated by the high dilution) where the BoNT-A can alter rates of biosynthesis of collagen and production of inflammatory cytokines. 50 …”

Section: Aesthetic Developmentsmentioning

confidence: 99%

See 1 more Smart Citation

New Uses of AbobotulinumtoxinA in Aesthetics

Schlessinger¹,

Gilbert²,

Cohen³

et al. 2017

Aesthetic Surgery Journal

View full text Add to dashboard Cite

BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance. These may be achieved through use of combinations of BoNT-A with other aesthetic procedures, tailoring the dose of toxin to the patient’s muscle mass or by using novel injection and application techniques. Beyond amelioration of facial lines, encouraging results have been seen with the use of BoNT-A to improve the appearance of hypertrophic and keloid scars and even to prevent them. Studies have been conducted with scars in various parts of the body and further research is ongoing. Dermatological and other medical uses for BoNT-A are also active areas of research. Injections of BoNT-A have been shown to reduce signs and symptoms of acne, rosacea, and psoriasis, to reduce neuromuscular pain, and to bring about significant improvements in a number of rare diseases that are caused or exacerbated by hyperhidrosis. This paper reviews these new uses for BoNT-A, looking at the rationale for their use and discussing the results of published case studies and clinical trials. These areas have shown great promise to date, but more and larger clinical studies will be required before these treatments become a clinical reality. To this end details are also provided of clinical trials currently listed in the main clinical trials database to highlight research areas of particular interest.

show abstract

“…Botulinum toxin A (BoNTA) injection is the most popular non‐invasive aesthetic procedure used to relax hyperkinetic musculature in face and neck. It blocks release of neurotransmitters such as acetylcholine (Ach), substance P, noradrenaline, vasoactive intestinal peptide (VIP), and calcitonin gene‐related peptide (CGRP) at the neuromuscular junction 1–26 . Advantages are no downtime, rapid onset of effect, and high patient satisfaction.…”

Section: Introductionmentioning

confidence: 99%

Employing microbotox technique for facial rejuvenation and face‐lift

Iranmanesh

Khalili

Mohammadi

et al. 2022

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Background Microbotox technique, intradermal injection of microdroplets of botulinum toxin, is a favorable rejuvenation approach in subjects who prefer more natural appearance. Aim To determine the best injection techniques (dosage, concentration, as well as number and location of injection points), efficacy and side effects of this innovative technique for facial rejuvenation. Methods We conducted a search in Pubmed, Embase, Web of Science, and Google Scholar databases from conception until October 2021 with keywords “microbotox” OR “mesobotox” OR “intradermal injection” AND “botulinum toxin” AND “rejuvenation” AND “wrinkle” AND “face‐lift.” Results Twenty articles were included in this review article. Different types of formulation including onabotulinum toxin A (OBA), abobotulinum toxin A (ABO), and incobotulinum toxin A (IBA) were used. The most used concentrations were 10–20 u/cc of OBA. Number of injection points varied from 4 (forehead and periorbital areas) to 999 (entire face) with 2 mm to 2 cm apart. Adjuvant treatment modalities were cross‐linked hyaluronic acid, intense pulsed laser, and Fraxel laser. Most studies reported the initial results appeared after 5–14 days of procedure, lasting for nearly 3–6 months. Conclusion Microbotox is an efficient and attractive method for facial rejuvenation, mid‐lower face‐lifting, and fine wrinkles reduction in forehead, periocular, and cheek regions, especially in younger‐aged subjects. Furthermore, it is a suitable treatment for neck rejuvenation and recontouring of lower mandibular border, particularly in older subjects with marked skin laxity.

show abstract

Accordion Wrinkle Treatment Through the Targeted Use of Botulinum Toxin Injections

Abstract: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Cited by 9 publications

References 21 publications

Anatomical contribution of the orbicularis oculi to the zygomaticus major: An improved understanding of the smile with consideration for facial cosmetic procedures

Anatomical contribution of the orbicularis oculi to the zygomaticus major: An improved understanding of the smile with consideration for facial cosmetic procedures

New Uses of AbobotulinumtoxinA in Aesthetics

Employing microbotox technique for facial rejuvenation and face‐lift

Contact Info

Product

Resources

About