Accommodative Performance of Children With Unilateral Amblyopia

Manh, Vivian; Chen, Angela M.; Tarczy-Hornoch, Kristina; Cotter, Susan A.; Candy, T. Rowan

doi:10.1167/iovs.14-14948

Cited by 35 publications

(27 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 21 ] It is known that the amblyopic eyes have lower accommodative amplitudes. [ 22 ] Because the intrinsic choroidal neurons are found in close contact with the contractile nonvascular smooth muscle cells and receive a copy of the signal sent to the ciliary body during accommodation, it has been hypothesized that the nonvascular smooth muscle cells are involved in the modulation of the choroidal thickness to stabilize the foveal position during accommodation. [ 23 ]…”

Section: Discussionmentioning

confidence: 99%

Choroidal Structure in Children with Anisohypermetropic Amblyopia Determined by Binarization of Optical Coherence Tomographic Images

et al. 2016

View full text Add to dashboard Cite

PurposeTo compare the choroidal structure of the subfoveal area in the eyes of children with anisohypermetropic amblyopia to that of the fellow eyes and to age-matched controls using a binarization method of the images obtained by enhanced depth imaging optical coherence tomography (EDI-OCT).MethodsThis study was performed at Nara Medical University Hospital, Tokushima University Hospital, and Kagoshima University Hospital, Japan. Forty amblyopic eyes with anisohypermetropic amblyopia and their fellow eyes (5.9 ± 2.1 years, mean ± standard deviation), and 103 age-matched controls (6.7 ± 2.4 years) were studied. The control eyes were divided into myopic, emmetropic, and hyperopic eyes. The total choroidal area, luminal area and stromal area of the subfoveal choroid were measured by the binarization method. The luminal/stromal ratio and the axial length of the amblyopic eyes were compared to that of the control eyes.ResultsThe total choroidal area in the amblyopic eyes was significantly larger than that of the fellow eyes (P = 0.005). The luminal/stromal ratio was significantly larger in the amblyopic eyes than that of the fellow eyes (P<0.001) and the control hyperopic eyes (P<0.001). There was a significant negative correlation between the luminal/stromal ratio and the axial length in the control eyes (r = -0.30, P = 0.001), but no significant correlation was found in the amblyopic eyes.ConclusionsThe choroidal structure of the amblyopic eyes was different from that of the fellow and the control hyperopic eyes. The choroidal changes are related to amblyopia.

show abstract

Section: Discussionmentioning

confidence: 99%

Choroidal Structure in Children with Anisohypermetropic Amblyopia Determined by Binarization of Optical Coherence Tomographic Images

et al. 2016

View full text Add to dashboard Cite

show abstract

“…When tested under monocular viewing conditions, the amblyopic eye is reported to have reduced amplitude and less accurate accommodation than the fellow eye and when compared with control subjects, particularly at higher accommodative demand fixation distance; however, the inter‐ocular difference in accommodative response is minimal (< 0.10 D) under binocular viewing …”

Section: Visual Deficits In Amblyopiamentioning

confidence: 99%

The functional impact of amblyopia

Webber

2018

Clinical and Experimental Optometry

View full text Add to dashboard Cite

Amblyopia is the most common disorder managed in paediatric ophthalmic practice in industrialised countries. Reports on the impact of amblyopia on tasks relevant to the activities of children, or on skills pertinent to their education and quality of life, is leading to greater understanding of the functional disabilities associated with the condition. This review considers the extent to which amblyopia affects the ability to carry out everyday tasks, with particular attention to studies of motor skills and reading proficiency in children. Collectively, these studies show that amblyopia results in poorer outcomes on tests of skills required for proficiency in everyday tasks and which relate to childhood academic performance. However, the relative contributions that the documented vision anomalies inherent in amblyopia contribute to various functional disabilities is not fully determined. Recent reports have demonstrated improvement following treatment in standardised measures of fine motor skills involved in practical, everyday tasks. Including measurement of functional performance skills in amblyopia treatment trials is desirable to show treatment effect on crucial, real-world activities.

show abstract

“…Functional amblyopia is a visual developmental disorder consisting of reduced best-corrected visual acuity in one or rarely in both eyes without the presence of any ocular pathology [1]. Due to the abnormalities in visual processing occurring in amblyopia, there are also deficits in contrast sensitivity, accommodation, binocular vision, fixation, saccades, color, and form and motion perception, among others [2][3][4][5][6][7][8][9]. ere are four types of amblyopia depending on its etiology: anisometropic amblyopia, strabismic amblyopia, mixed amblyopia (if anisometropia and strabism coexist), and deprivation amblyopia (if there was pathology during visual development which struggled the eye stimulation) [7].…”

Section: Introductionmentioning

confidence: 99%

Active Vision Therapy for Anisometropic Amblyopia in Children: A Systematic Review

Hernández-Rodríguez

Piñero

2020

Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose. The aim of the study was evaluation of the scientific evidence about the efficacy of vision therapy in children and teenagers with anisometropic amblyopia by performing a systematic literature review. Methods. A search was performed using 3 searching strategies in 4 different databases (PubMed, Web of Science, Scopus, and PruQuest). The quality of the included articles was evaluated using two tools for the risk of bias assessment, ROBINS-I for nonrandomized studies of intervention (NRSI), and ROB 2.0 for randomized clinical trials. Results. The search showed 1274 references, but only 8 of them passed the inclusion criteria after the complete text review. The articles that were finally included comprised 2 randomized control trials and 6 nonrandomized studies of intervention. These articles provided evidence supporting the efficacy of vision therapy for the treatment of anisometropic amblyopia in children and teenagers. Assessment of the risk of bias showed an appropriate risk of bias for the randomized control trials, but a high risk of bias for nonrandomized studies of intervention (NRSI). A main source of risk of bias for NRSI was the domain related to the measurements of the outcomes, due to a lack of double-blind studies. Conclusion. Vision therapy is a promising option for the treatment of anisometropic amblyopia in children and teenagers. However, the level of scientific evidence provided by the studies revised is still limited, and further randomized clinical trials are necessary to confirm the results provided to date and to optimize the vision therapy techniques by knowing the specific neural mechanisms involved.

show abstract

Accommodative Performance of Children With Unilateral Amblyopia

Abstract: When viewing monocularly, children with unilateral amblyopia had greater mean accommodative errors in their amblyopic eyes than in their nonamblyopic eyes, and when compared with control subjects. This could lead to unintended retinal image defocus during patching therapy for amblyopia.

Cited by 35 publications

References 61 publications

Choroidal Structure in Children with Anisohypermetropic Amblyopia Determined by Binarization of Optical Coherence Tomographic Images

Choroidal Structure in Children with Anisohypermetropic Amblyopia Determined by Binarization of Optical Coherence Tomographic Images

The functional impact of amblyopia

Active Vision Therapy for Anisometropic Amblyopia in Children: A Systematic Review

Contact Info

Product

Resources

About