Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery

Ong, Hon Shing; Evans, Jennifer R; Allan, Bruce

doi:10.1002/14651858.cd009667.pub2

Cited by 40 publications

(23 citation statements)

References 31 publications

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“…Posterior capsular opacification and capsular contraction resulting in asymmetric vaulting and lens tilt have been reported with the AT-45 Crystalens (Eyeonics Vision, Alisa Viejo, CA) and 1CU IOL (HumanOptics, Erlangen, Germany). 1 …”

Section: Multifocal and Accommodating Strategiesmentioning

confidence: 99%

Extended Depth of Focus IOLs: The Next Chapter in Refractive Technology?

Rocha¹

2017

J Refract Surg

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Section: Multifocal and Accommodating Strategiesmentioning

confidence: 99%

Extended Depth of Focus IOLs: The Next Chapter in Refractive Technology?

Rocha¹

2017

J Refract Surg

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“…However, a majority of IOLs are manufactured from acrylic polymers (hydrophobic and hydrophilic acrylate or methacrylate polymers) with extremely rigid structures; hence, the eye loses its ability to accommodate to various distances 2,4 . Therefore, patients with monofocal IOL implants are dependent on spectacles for near vision (e.g., while reading a newspaper or a book) 5 . Different approaches to restoring the accommodation ability after cataract surgery have been reported.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Riehle

Thude

Kandelbauer

et al. 2019

JoVE

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This study discusses a synthesis route for soft polysiloxane-based urea (PSU) elastomers for their applications as accommodating intraocular lenses (a-IOLs). Aminopropyl-terminated polydimethylsiloxanes (PDMS) were previously prepared via the ring-chain equilibration of the cyclic siloxane octamethylcyclotetrasiloxane (D 4) and 1,3-bis(3-aminopropyl)-tetramethyldisiloxane (APTMDS). Phenyl groups were introduced into the siloxane backbone via the copolymerization of D 4 and 2,4,6,8-tetramethyl-2,4,6,8-tetraphenyl-cyclotetrasiloxane (D 4 Me,Ph). These polydimethylmethyl-phenyl-siloxane-block copolymers were synthesized for increasing the refractive indices of polysiloxanes. For applications as an a-IOL, the refractive index of the polysiloxanes must be equivalent to that of a young human eye lens. The polysiloxane molecular weight is controlled by the ratio of the cyclic siloxane to the endblocker APTMDS. The transparency of the PSU elastomers is examined by the transmittance measurement of films between 200 and 750 nm, using a UV-Vis spectrophotometer. Transmittance values at 750 nm (upper end of the visible spectrum) are plotted against the PDMS molecular weight, and > 90% of the transmittance is observed until a molecular weight of 18,000 g•mol −1. Mechanical properties of the PSU elastomers are investigated using stress-strain tests on die-cut dog-bone-shaped specimens. For evaluating mechanical stability, mechanical hysteresis is measured by repeatedly stretching (10x) the specimens to 5% and 100% elongation. Hysteresis considerably decreases with the increase in the PDMS molecular weight. In vitro cytotoxicity of some selected PSU elastomers is evaluated using an MTS cell viability assay. The methods described herein permit the synthesis of a soft, transparent, and noncytotoxic PSU elastomer with a refractive index approximately equal to that of a young human eye lens.

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“…This structure gains variable refractive ability with ciliary muscle help, being able to adjustments in its thickness according to the distance of the focused object, mechanism called accommodation. The contraction of the muscle provides increased crystalline curvature, which makes larger dioptric power of the visual system and allow near vision [1,2,3].…”

Section: Introductionmentioning

confidence: 99%

“…The improvement of the surgical techniques, as well as the evolution of intraocular lenses, provide alternatives to correct two above mentioned diseases -cataract and presbyopia -upon the same procedure. At present, good view for different distances, without glasses dependence, can be obtained through implants of bifocal, trifocal or multifocal lenses after phacoemulsification surgery [1,2,5].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2017

JOCR

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Introduction:Cataract surgery with intraocular multifocal lens (IOML) implant allows visual recovery for different distances, regardless of the use of external correction, despiteits undesirable effects. The visual function has impact on quality of life, as on the ability to perform daily activities and on the patient satisfaction. Objectives: Evaluate satisfaction and quality of vision in patients who underwent phacoemulsification surgery with implant of multifocal intraocular lens, even with the eyewear independence and with the presence of adverse effects.Methods: An observational, descriptive and retrospective study was carried out with patients undergoing phacoemulsification surgery with IOML implantation at a private clinic in Florianópolis (Brazil) from January 2009 to December 2015. Objective data were collected from electronic medical records and the questionnaire "TyPEqustionnaire" was completed for subjective analysis, through telephone calls. Afterwards, the data were submitted to descriptive statistical analysis and the corresponding variables were correlated through the Pearson chi-square test, with a significance level of p <0.05 being considered.Results: A total of 436 cataract surgeries were performed with IOML implantation in 223 patients. Ninety-nine patients were excluded either because they did not complete the inclusion criteria list or because of the impossibility of being reached by telephone contact. Thus, 124 patients effectively participated in the study. There was a higher prevalence of women (79%), and a non-toric aspheric lens implant (65%). The average age was 64 years and all patients were residents in the Santa Catarina state. The mean score for far distance vision was 8.35; for intermediate distance vision was 8.43 and for near distance vision was 7.87; at a rate from 0 to 10, being equivalent to unsatisfactory and very satisfied visual acuity, respectively. Glare was reported in 44,30% of patients, halos during the day were verified in 20,60% of the sample and halo-related complaint at night in 35,48% of the patients. Conclusion:In the final assessment of the questionnaire it was found that the patients were satisfied with the visual acuity after IOML implant. There was a moderate incidence of undesirable photopic effects and little dependence on glasses. IOML may be a good choice when immersed in real expectation for patients who want vision improvement without eyewear. In addition, the good relationship between surgeon and patient and the informed consent about the procedure are very important to the patient's satisfaction with the final visual result as well.

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Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery

Abstract: Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery.

Cited by 40 publications

References 31 publications

Extended Depth of Focus IOLs: The Next Chapter in Refractive Technology?

Extended Depth of Focus IOLs: The Next Chapter in Refractive Technology?

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

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