Access to Intrinsically Glucoside‐Based Microspheres with Boron Affinity

Abstract

Intrinsically glucoside-based microspheres are prepared in olive oil via a water in oil inverse suspension polymerization. The microspheres are characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) microscopy, and X-ray photoelectron spectroscopy (XPS), evidencing the intrinsic glucose character of the spheres. A novel boronic acid fluorescent molecule was subsequently conjugated to the microspheres in an aqueous environment, exhibiting the spatial and uniform distribution of glucoside as well as the affinity of the microspheres to bind with boron, evidenced via fluorescence spectroscopy measurements.

Photo-Sensitive RAFT-Agents for Advanced Microparticle Design

“…Furthermore, the C 1s peak in the XP spectra can be deconvoluted into several components (see Figure S 40): one at 285.0 eV (C–C, C–H), a second one at 286.5 eV (C–O, C–N), and a third one at 288.9 eV (O–CO, N–CO) . The ratios of the intensities of the carbon peaks at 285.0 eV (C–C, C–H) and 286.5 eV (C–O, C–N) is depicted in Figure together with additional results from EA which will be discussed in detail below.…”

“…In the case of grafted-on PDMAA amide groups are introduced on the microspheres. Amide vibrations have a band in the IR spectrum which can be distinguished from the ester vibrations . Therefore, high resolution attenuated total reflectance (ATR) FT-IR microscopy can be employed to not only show the successful grafting, yet also its spatial distribution.…”

“…Amide vibrations have a band in the IR spectrum which can be distinguished from the ester vibrations. 49 Therefore, high resolution attenuated total reflectance (ATR) FT-IR microscopy can be employed to not only show the successful grafting, yet also its spatial distribution. FT-IR microscopy has been employed before to evidence the successful grafting onto microspheres, 31 and can furthermore even give quantitative information about grafting reactions.…”

Photo‐Induced Functionalization of Spherical and Planar Surfaces via Caged Thioaldehyde End‐Functional Polymers

“…High resolution FT‐IR microscopy can be employed to determine the spatial distribution as well as the amount of IR‐active groups on microspheres and on flat substrates . Since PDMAA contains an amide exhibiting an IR band that can readily be distinguished from the ester vibration of the PGMA spheres, IR microscopy is an elegant tool to show the successful and evenly distributed grafting of PDMAA onto microspheres, as evidenced in Figure .…”

“…Microspheres have a wide range of applications from pharmaceuticals and chromatography to organic synthesis . Although variable functionalities can already be incorporated during the microsphere synthesis, significant interest lies in grafting polymeric chains onto the particles in order to introduce tailored functionalities and properties …”