Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial

Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis

“…Where follow-up data were available, initial gains were sustained at each follow-up point following the ACT intervention for QoL, mood and ACT-targeted processes (1). Conversely, Meek et al (2021) reported no significant effect on the outcomes of interest, which was also demonstrated at 12-week follow-up. Nordin and Rorsman (2012) reported an effect on AAQ-II within the ACT arm, which was maintained at longer-term follow-up.…”

“…Across studies, there were small sample sizes with studies reporting a lack of power and a high attrition rate, limiting the confidence in the results (Meek et al, 2021). This issue which is commonly reported within psychological intervention studies on this population (Thomas et al, 2006).…”

“…Sesel et al (2018) found CBT to be less efficacious in comparison to other psychological interventions (e.g., progressive muscle relaxation and mindfulness) for anxiety, depression, fatigue, pain and QoL of pwMS. Sesel et al (2018) suggested CBT is potentially unsuitable for the MS population due to the emphasis on learning strategies and completing certain homework tasks that can be challenging given cognitive impairment is common in MS. Further, CBT's focus on challenging negative thoughts has been criticised as invalidating, given these thoughts are likely to be realistic and logical within chronic, unpredictable conditions, such as MS (Meek et al, 2021). Therefore, there is an impetus to develop and evaluate other types of psychological therapies for pwMS.…”