Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework

Sekhon, Mandeep; Cartwright, Martin; Francis, Jill J

doi:10.1186/s12913-017-2031-8

Cited by 2,201 publications

(3,031 citation statements)

References 69 publications

(71 reference statements)

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“…Acceptability of a therapy reflects the extent to which patients consider it appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention. 18 This further depends on the affective attitude, burden, perceived effectiveness, ethicality, intervention coherence, opportunity costs, and selfefficacy. Since 2016, FMT has been offered to 129 corticosteroid, thiopurine and biologic-exposed patients with active UC.…”

Section: Discussionmentioning

confidence: 99%

Acceptability, tolerability, and safety of fecal microbiota transplantation in patients with active ulcerative colitis (AT&S Study)

Sood

Singh

Mahajan

et al. 2019

J of Gastro and Hepatol

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Background and Aim Fecal microbiota transplantation (FMT) targets gut microbiome dysbiosis and is an emerging therapy for ulcerative colitis (UC). Although initial results with FMT in patients with active UC are encouraging, data regarding its acceptability, tolerability, and safety are scant. Methods A retrospective analysis of patients with active UC (Mayo clinic score ≥ 4), who received multisession FMT (at weeks 0, 2, 6, 10, 14, 18, and 22) via colonoscopy between June 2016 and June 2018, was performed. Patient acceptability, tolerability, and immediate and long‐term safety of the therapy were assessed. Results Of the 129 patients with active UC who were offered FMT, 101 patients consented, giving acceptability of 78.3%. Fecal slurry retention time improved with each session (3.27 ± 1.06 h for the first session vs 5.12 ± 0.5 h for the seventh session). Abdominal discomfort, flatulence, abdominal distension, borborygmi, and low‐grade fever (30.8%, 15.9%, 9.8%, 7.9%, and 7.6%, respectively) were the most common post‐procedural short‐term adverse events. Long‐term adverse events included new‐onset urticaria (n = 2, 4.3%), arthritis/arthralgia (n = 3, 6.5%), depression (n = 1, 2.2%), partial sensorineural hearing loss (n = 1, 2.2%), and allergic bronchitis (n = 1, 2.2%). Thirteen (12.9%) patients dropped out because of adverse events. Conclusion Fecal microbiota transplantation appears to be a safe and well‐tolerated procedure, with good acceptability in patients with active UC.

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Section: Discussionmentioning

confidence: 99%

Acceptability, tolerability, and safety of fecal microbiota transplantation in patients with active ulcerative colitis (AT&S Study)

Sood

Singh

Mahajan

et al. 2019

J of Gastro and Hepatol

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“…For this nested qualitative study, convenience sampling was used to recruit participants for a semi‐structured interview. Sekhon and colleagues’ “Theoretical Framework of Acceptability,” informed the development of the interview schedule. Participants were reimbursed AUD20.…”

Section: Methodsmentioning

confidence: 99%

Community‐based, point‐of‐care hepatitis C testing: perspectives and preferences of people who inject drugs

Latham

Pedrana

Doyle

et al. 2019

Journal of Viral Hepatitis

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Summary A barrier to hepatitis C treatment for people who inject drugs (PWID) is needing to attend multiple appointments for diagnosis. Point‐of‐care hepatitis C tests provide results within 20 to 105 minutes and can be offered opportunistically in nonclinical settings such as needle syringe programmes. In this nested qualitative study, we explored the acceptability of point‐of‐care testing for PWID. PWID attending participating needle syringe programmes were screened using the OraQuick HCV antibody mouth swab (result in 20 minutes); those with a reactive result then underwent venepuncture for a point‐of‐care RNA test: the Xpert HCV Viral Load (result in 105 minutes). Convenience sampling was used to select participants for a semi‐structured interview. A hybrid thematic analysis was performed, guided by Sekhon's “Theoretical Framework of Acceptability.” Nineteen participants were interviewed. Three core themes emerged: "people and place," "method of specimen collection," and "rapidity of result return." It was highly acceptable to be offered testing at the needle syringeprogrammes by nurses and community health workers, who were described as competent and nonjudgemental. Most participants reported that even if a finger‐stick point‐of‐care RNA test were an option in the future, they would prefer venepuncture, as the sample could be used for pre‐treatment workup and bundled testing. Waiting 20 minutes to receive the antibody test result was acceptable, whereas the 105 minutes required for the RNA result was unacceptable. Offering point‐of‐care hepatitis C testing at needle syringe programmes is acceptable to PWID, however tests that avoid venepuncture are not necessarily the most attractive to PWID.

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“…This could indicate that HVs in this RCT, even though they had received detailed training and regular supervision, might not feel competent, confident or comfortable in offering the designated intervention. Acceptability of the intervention to both the intervention provider and recipient is important because it determines engagement and outcomes (Sekhon, Cartwright, & Francis, ).…”

Section: Discussionmentioning

confidence: 99%

Using the TIDieR checklist to describe health visitor support for mothers with mental health problems: Analysis of a cross‐sectional survey

Lowenhoff

Davison-Fischer

Pike

et al. 2019

Health Soc Care Community

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At least half of the 20% of mothers who experience mental health problems (MHPs) during pregnancy or after birth are not receiving the help they need that will lead to recovery. In order to identify where improvements need to be made, it is necessary to describe exactly what is being done and the barriers and facilitators that compromise or enhance optimal care. The majority of mothers experience mild to moderate anxiety or depression. The expectation is that primary care professionals, such as health visitors (HVs), can provide the support they need that will lead to recovery. The aim of this study was to explore the views of HVs regarding the content and purpose of an intervention to support mothers with MHPs, described as ‘listening visits’ (LVs). A link to an online survey was offered to the members and champions of the Institute of Health Visiting (n = 9,474) March–May 2016. The survey was completed by 1,599 (17%) of the target population, of whom 85% were offering LVs. The Template for Intervention Description and Replication (TIDieR) checklist was used to provide a framework to describe commonalities and variations in practice. There appeared to be a shared understanding of the rationale for LVs but a lack of agreement about what the intervention should be called, the techniques that should be used and the duration, frequency and expected outcomes of the intervention. Contextual factors such as staff shortages; conflicting priorities; the needs and circumstances of mothers; the capability and motivation of HVs; inadequate training and supervision; and the absence of clear guidance contributed to variations in perceptions and practice. There are many ways in which the HV contribution to the assessment and management of mothers with MHPs could be improved. The intervention delivered by HVs needs to be more clearly articulated. The contextual factors influencing competent and consistent practice also need to be addressed.

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Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework

Cited by 2,201 publications

References 69 publications

Acceptability, tolerability, and safety of fecal microbiota transplantation in patients with active ulcerative colitis (AT&S Study)

Acceptability, tolerability, and safety of fecal microbiota transplantation in patients with active ulcerative colitis (AT&S Study)

Community‐based, point‐of‐care hepatitis C testing: perspectives and preferences of people who inject drugs

Using the TIDieR checklist to describe health visitor support for mothers with mental health problems: Analysis of a cross‐sectional survey

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