Accelerating Strain Engineering using Desorption Electrospray Ionization-Imaging Mass Spectrometry and Untargeted Molecular Analysis of Intact Microbial Colonies
Abstract:Progress in the fields of genomic and biologic sciences has yielded microbial bioprocesses for the advanced production of chemicals. While biomanufacturing has the potential to address global demands for renewable fuels and chemicals, engineering microbial cell factories that can compete with synthetic chemical processes remains a challenge. Optimizing strains for enhanced chemical production is no longer limited by reading and writing DNA, rather it is impeded by the lack of high-throughput platforms for char… Show more
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