Accelerated QRS widening as an independent predictor of cardiac death or of the need for heart transplantation in patients with congestive heart failure

Grigioni, Francesco; Carinci, Valeria; Boriani, Giuseppe; Bracchetti, Giovanni; Potena, Luciano; Magnani, Gaia; Reggiani, Maria Letizia Bacchi; Magelli, Carlo; Branzi, Angelo

doi:10.1016/s1053-2498(02)00431-x

Cited by 55 publications

(34 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Grigoni et al examined the ECGs of 82 patients with dilated cardiomyopathy and found that progressive QRS widening of 0.5 ms/month independently predicted death or the need for transplantation. 7 Our findings support those of previous reports associating increased QRS duration with poor outcome.…”

Section: Discussionsupporting

confidence: 92%

Electrocardiogram and clinical characteristics of patients referred for cardiac transplantation: Implications for pacing in heart failure

Freudenberger

Sikora

Fisher

et al. 2004

Clinical Cardiology

View full text Add to dashboard Cite

SummaryBackground: Permanent pacing for the treatment of heart failure (HF) has been the subject of intense research over the past decade. Those with conduction abnormalities may benefit most from pacing. The incidence of these conduction abnormalities in patients referred for cardiac transplantation and its relationship to outcome has not been well described.Hypothesis: This study sought to determine the incidence of these abnormalities and to correlate these findings to outcome in this patient population.Methods: A review of 100 patients referred for transplantation was performed. Data were analyzed in two groups: those with QRS duration < 120 ms and those with a QRS duration > 120 ms. Times to transplantation or death were analyzed in these two groups.Results: Of these patients, 34% had QRS duration ≥ 120 ms and survival was inversely associated with QRS duration. Of those with QRS duration < 120 ms, 24% (16) went on to cardiac transplantation or died. Of those with a QRS duration ≥ 120 ms, 55% (17) went on to transplantation or died (p = 0.0134).Conclusions: This suggests that in addition to a multi-drug regimen for heart failure, 34% of patients referred for transplantation may benefit from additional therapy with biventricular pacing.

show abstract

Section: Discussionsupporting

confidence: 92%

Electrocardiogram and clinical characteristics of patients referred for cardiac transplantation: Implications for pacing in heart failure

Freudenberger

Sikora

Fisher

et al. 2004

Clinical Cardiology

View full text Add to dashboard Cite

show abstract

“…4,5 In patients with dilated cardiomyopathy, QRS duration increases progressively. 3,27 This indicates that even in the presence of complete bundle-branch block, increased left ventricular mass with increased CV may cause an increase in QRS duration, although it cannot be excluded that conduction is slowed in more severe HF. Indeed, in a study of individuals free of HF and myocardial infarction, QRS duration was positively correlated with left ventricular mass and dimensions.…”

Section: Qrs Durationmentioning

confidence: 99%

Larger Cell Size in Rabbits With Heart Failure Increases Myocardial Conduction Velocity and QRS Duration

et al. 2006

View full text Add to dashboard Cite

show abstract

“…27 This suggests that in contrast to absolute values, the relative changes in QTc interval measured from standard ECGs obtained at the time of an annual angiography can serve as a predictor of long-term outcome after heart transplantation.…”

Section: Changes In Qtc Duration and Long-term Outcomementioning

confidence: 99%

Prognostic Value of the QTc Interval after Cardiac Transplantation

Vrtovec

Radovancevic

Thomas

et al. 2006

The Journal of Heart and Lung Transplantation

View full text Add to dashboard Cite

Accelerated QRS widening as an independent predictor of cardiac death or of the need for heart transplantation in patients with congestive heart failure

Cited by 55 publications

References 9 publications

Electrocardiogram and clinical characteristics of patients referred for cardiac transplantation: Implications for pacing in heart failure

Electrocardiogram and clinical characteristics of patients referred for cardiac transplantation: Implications for pacing in heart failure

Larger Cell Size in Rabbits With Heart Failure Increases Myocardial Conduction Velocity and QRS Duration

Prognostic Value of the QTc Interval after Cardiac Transplantation

Contact Info

Product

Resources

About