Accelerated long-term forgetting in temporal lobe epilepsy: Verbal, nonverbal and autobiographical memory

Narayanan, Jwala; Duncan, Rod; Greene, J; Leach, John Paul; Razvi, Saif; McLean, John M.; Evans, Jonathan J.

doi:10.1016/j.yebeh.2012.06.038

Cited by 44 publications

(28 citation statements)

References 26 publications

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“…We also note that in other forgetting studies in epilepsy, some did not find statistically significant accelerated forgetting (Davidson, Dorris, O'Regan, & Zuberi, 2007;Mulhert et al, 2011;Narayanan et al, 2012) and others only observed accelerated forgetting after longer delays (Evans et al, 2014;Tramoni et al, 2011). Whilst heterogeneity of method and materials are likely to have contributed to the variability of M A N U S C R I P T…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 61%

“…There is little other research finding a similar association; the exception being Narayanan et al (2012), who found a similar trend for faster long-term visual forgetting in those with right-hemisphere TLE by four weeks. However, they did not measure long-term recall at any earlier delay, thus we cannot elucidate whether accelerated forgetting could have been detectable earlier.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 91%

“…Further, it is evident in the majority of studies that the precise period over which accelerated forgetting manifested was often reflective of the time points measured: most found faster forgetting by the first or second delay interval measured after learning of new material (see Table 1, Delay Trials column). Moreover, some studies did not report learning performance (Dewar, Hoefeijzers, Zeman, Butler, & Della Sala, 2015;Gallassi et al, 2011;Hoefeijzers, Dewar, Dalla Sala, Butler, & Zeman, 2014;Jansari, Davis, McGibbon, Firminger, & Kapur, 2010;Lah, Mohamed, Thayer, Miller, & Diamond, 2014;McGibbon & Jansari, 2013;Narayanan et al, 2012;O'Connor, Sieggreen, Ahern, Schomer, & Mesulam, 1997;Ricci, Mohamed, Savage, Boserio, & Miller, 2015;Tramoni et al, 2011). In others, learning performance was not equated (Bell, 2006;Bell, Fine, Dow, Seidenberg, & Hermann, 2005;Cronel-Ohayon et al, 2006;Giovagnoli, Casazza, & Avanzini, 1995;Holdstock, Mayes, Isaac, Gong, & Roberts, 2002;Lucchelli & Spinnler, 1998;Mameniskiene et al, 2006;Mayes et al, 2003).…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

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Forgetting in temporal lobe epilepsy: When does it become accelerated?

Cassel

Morris

Koutroumanidis

et al. 2016

Cortex

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The notion of 'accelerated long-term forgetting' has often been attributed to disrupted 'late' memory consolidation. Nevertheless, methodological issues in the literature have left this theory unproven, leading some to suggest such findings may be reflective of subtle acquisition or early retention deficits. This study attempts to address such issues, and also to explore which pathophysiological variables are associated with forgetting rates. Eighteen participants with temporal lobe epilepsy (TLE) and eighteen matched controls completed background neuropsychological measurement of immediate and short-delay memory that showed comparable performance, both on verbal and visual tests. Using two novel experimental tasks to measure long-term forgetting, cued recall of verbal and visuospatial material was tested 30 seconds, 10 minutes, one day, and one week after learning. Forgetting of verbal material was found to be progressively faster during the course of a week in the TLE group. For visuospatial memory, participants in the TLE group exhibited faster early forgetting in the first 10 minutes after learning, as indicated by planned comparisons, with comparable forgetting rates thereafter. Our findings provide evidence for two patterns of disruption to 'early' memory consolidation in this population, occurring either at the initial delay only or continuing progressively through time. Differences in how soon after learning accelerated forgetting was detectable were related to factors associated with greater severity of epilepsy, such as presence of medial temporal lobe sclerosis on MRI and use of multiple anti-epileptic agents.

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Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 61%

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 91%

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

See 1 more Smart Citation

Forgetting in temporal lobe epilepsy: When does it become accelerated?

Cassel

Morris

Koutroumanidis

et al. 2016

Cortex

View full text Add to dashboard Cite

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“…Por otra parte también se pueden deber a problemas en la adquisición de información, que puede pasar desapercibida si se examina el aprendizaje después de cortos períodos de tiempo (25).…”

Section: F Lázaro E Marín M Condeunclassified

“…Trabajos más recientes proponen que esto se debe a una posible reorganización, a modo de proceso compensatorio, de los procesos mnésicos al hemisferio contralateral (25). Esta teoría apoya la participación bilateral de los lóbulos temporales como condición necesaria para causar alteraciones de memoria en este grupo de pacientes.…”

Section: Anatomía Patológicaunclassified

Neuropsiquiatría clínica de la epilepsia: la amnesia epiléptica transitoria. A propósito de un caso

Perlado

Diaz-Guardamino

Rivas

2014

Rev. Asoc. Esp. Neuropsiq.

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RESUMEN: Introducción: Muchos pacientes epilép-ticos refieren problemas mnésicos. Encontramos un grupo de pacientes que presentan episodios amnési-cos de repetición y problemas en la memoria autobiográfica. Este cuadro clínico ha sido definido como "amnesia epiléptica transitoria". Tras revisar la literatura, describimos las características de esta entidad nosológica con detalle. Caso clínico: Informamos de un caso de amnesia epiléptica transitoria en un varón de 58 años, con un diagnóstico previo de epilepsia y cuadro afectivo, que presenta episodios recurrentes y transitorios de amnesia mostrando el resto de sus funciones cognitivas preservadas. Durante los ataques se describen automatismos oro-alimentarios, breves ataques de estupor sin pérdida de consciencia ni desconexión con el medio. Conclusiones: La amnesia epiléptica transitoria es un subtipo de epilepsia del lóbulo temporal bien definido pero infradiagnosticado. En casos de pacientes que refieren únicamente problemas de memoria, sobre todo si son episodios de amnesia breves y recurrentes, y en aquéllos pacientes que refieran deficiencias en la memoria remota, la amnesia epiléptica transitoria debe ser considerada como una opción diagnósti-ca seria. El tratamiento con fármacos anticomiciales produce muy buenos resultados.

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Neuropsychological testing in presurgical evaluation

Jones‐Gotman

Djordjević

2015

The Treatment of Epilepsy

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Accelerated long-term forgetting in temporal lobe epilepsy: Verbal, nonverbal and autobiographical memory

Cited by 44 publications

References 26 publications

Forgetting in temporal lobe epilepsy: When does it become accelerated?

Forgetting in temporal lobe epilepsy: When does it become accelerated?

Neuropsiquiatría clínica de la epilepsia: la amnesia epiléptica transitoria. A propósito de un caso

Neuropsychological testing in presurgical evaluation

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