Accelerated growth performance and stable germ-line transmission in androgenetically derived homozygous transgenic mud loach, Misgurnus mizolepis

Developmental biotechnology for aquaculture, with special reference to surrogate production in teleost fishes

“…If we can get the PGCs from the offspring of the survivor, in which genes for disease resistance are expected, after mass mortality, we could easily increase the number of fish-seed with disease tolerance. Transgenic techniques were developed to enhance growth in several fish species (Devlin et al, 1994;Nam et al, 2001Nam et al, , 2002. If the generation time is shortened, these transgenic lines are useful candidates for surrogate parents for rapid propagation and breeding of fish-seed.…”

“…Chromosome set manipulation techniques make it possible to realize sex-manipulation, sterilization and establishment of inbred stains by cloning (Arai, 1997). Transgenic techniques were also developed to enhance growth (Devlin et al, 1994;Nam et al, 2001Nam et al, , 2002. Genetic infrastructures, such as whole genome sequencing, linkage mapping and EST, are required for further improvement by maker-assisted selection, but at present only exist for a limited number of aquaculture species (Taniguchi, 2000;Coimbra et al, 2003;Ohara et al, 2005).…”

Increased food intake in growth hormone-transgenic common carp (Cyprinus carpio L.) may be mediated by upregulating Agouti-related protein (AgRP)

“…Since the first batch of transgenic fish was produced (Zhu et al, 1985), transgenesis has been used in many fish species (Hu and Zhu, 2010). To date, several stable lines of growth-enhanced transgenic fishes have been generated, including Atlantic salmon (Salmo salar) (Fletcher et al, 2004), coho salmon (Oncorhynchus kisutch) (Devlin et al, 2004), mud loach (Misgurnus mizolepis) (Nam et al, 2002), tilapia (Oreochromis sp.) (Martinez et al, 1999;Rahman et al, 1998) and common carp (Cyprinus carpio L.) (Wang et al, 2001;Zhong et al, 2012).…”

Antisense for gonadotropin-releasing hormone reduces gonadotropin synthesis and gonadal development in transgenic common carp (Cyprinus carpio)

“…The first transgenic fish were produced in the 1980s (Maclean and Talwar, 1984;Zhu et al, 1985), and since then modified fish have been produced with genetically desirable traits such as rapid growth, high feed conversion, disease resistance and cold tolerance (Zhang et al, 1990;Wang et al, 1995;Devlin et al, 2001;Rahman et al, 2001;Nam et al, 2001Nam et al, , 2002Zhong et al, 2002;Jhingan et al, 2003;Mao et al, 2004), all of which would prove beneficial commercially. However, these transgenic fish have not been implemented because if they were released into natural ecosystems, interbreeding could occur resulting in competition with native fish.…”