Acaricidal activity of the hyacinthacine analogues derived from pyrrolizidine alkaloids on Rhipicephalus (Boophilus) microplus

Duarte, Mônica Oliveira; Ferrarini, Stela Regina; Pazinatto, Mariane; Oliveira, Elise Botteselle de; Rolim, Verônica Machado; Eifler‐Lima, Vera Lucia; Ribeiro, Vera Lucia Sardá; Poser, Gilsane von

doi:10.1007/s00436-008-1022-4

Cited by 5 publications

(3 citation statements)

References 13 publications

(11 reference statements)

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“…After 24 h of treatment, the highest acaricidal activity of 70.8% was recorded in the ticks treated with 8% extract of A. squamosa followed by Nicotiana tobacum (45.8%) and Tamarindus indica (41.7%) extracts, while 29.8% and 20.8% mortality, respectively, was recorded in ticks treated with Eucalyptus globulus and Citrus limonum extracts against B. microplus (Magadum et al 2009)). Duarte et al (2008) have reported that effect of six hyacinthacine analogues derived from pyrrolizidine alkaloids were toxic to the larvae of the ticks and inhibited the eggs' hatchability at 5 μg/ml, and at the lowest concentration (0.625 μg/ml), some effect in the eggs' hatchability was observed against the cattle tick R. (B.)…”

Section: Discussionmentioning

confidence: 98%

Evaluation of medicinal plant extracts against ticks and fluke

Elango¹,

Rahuman²

2010

Parasitol Res

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The present study was based on assessments of the antiparasitic activities to determine the efficacies of leaf hexane, chloroform, ethyl acetate, acetone and methanol extracts of Aegle marmelos (Linn.) Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wallich ex Nees., Cocculus hirsutus (L.) Diels, Eclipta prostrata L., and Tagetes erecta L. against the adult cattle tick Haemaphysalis bispinosa Neumann 1897 (Acarina: Ixodidae), the larvae of Rhipicephalus (Boophilus) microplus Canestrini 1887 (Acari: Ixodidae) and sheep fluke Paramphistomum cervi Zeder 1790 (Digenea: Paramphistomatidae). All plant extracts showed moderate toxic effect on parasites after 24 h of exposure; however, the highest parasitic activity was found in leaf ethyl acetate extract of A. lineata, methanol extract of A. marmelos, A. paniculata, and C. hirsutus against H. bispinosa (LC(50) = 395.27, 358.45, 327.21 and 420.50 ppm); ethyl acetate extract of A. paniculata, C. hirsutus, methanol extracts of A. marmelos, A. lineata, and E. prostrata against the larvae of R. microplus (LC(50) = 207.70, 258.61, 134.09, 206.00, and 274.33 ppm); hexane extract of A. lineata, ethyl acetate extract of A. paniculata, E. prostrata, acetone extracts of T. erecta, methanol extracts of A. marmelos and C. hirsutus against P. cervi (LC(50) = 254.23, 451.17, 425.73, 253.60, 542.71, and 360.17 ppm), respectively. The present study is the first report on the veterinary parasitic activity of plant extracts from Southern India.

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Section: Discussionmentioning

confidence: 98%

Evaluation of medicinal plant extracts against ticks and fluke

Elango¹,

Rahuman²

2010

Parasitol Res

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“…All the larvae died at concentrations between 5.5 and 7.14% [34). Duarte et al [35] have reported that effect of six hyacinthacine analogues derived from pyrrolizidine alkaloids were toxic to the larvae of the ticks and inhibited the eggs' hatchability at 5μg/ml. The plant Sapindus saponaria also demonstrated larvicidal activity for the Rhipicephalus sanguineus (Acari: Ixodidae), with LC50 and LC99 values of 1,994 and 3,922 ppm, respectively [36].…”

Section: Discussionmentioning

confidence: 99%

Ectoparasiticidal Activity of Herbal Product Keetguard Liquid against Riphicephalus Microplus in Ruminants

Jumde¹

2013

JSRR

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Aims:The present study was aimed to determine the in vivo and in vitro efficacy of herbal ectoparasiticidal and fly repellant Keetguard liquid (Supplied by M/s Ayurvet Ltd. Baddi, HP, India) against Rhipicephalus microplus. Study Design: 24 non descript cows with natural and heavy tick infestation were selected for the trial and divided into four groups of 6 animals Group I, Group II, Group III and Group IV. Each group of animals was kept as control for specific period of time and thereafter they were treated with 1:20 dilution of Keetguard liquid applied over the body coat by spray method once a day and twice weekly. Place and Duration of Study: Study was conducted under field condition and was

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“…Several potentially therapeutic effects of hyacinthacine have been reported. For example, analogues of hyacinthacine are acaricidal, at least in vitro,7 and other actions have been described both in vitro and in animals.…”

Section: Hyacinthacinementioning

confidence: 99%

When I use a word . . . . Medical hyacinths

Aronson

2022

BMJ

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The word “vaccinia” refers not only to the orthopoxvirus used in vaccination against smallpox; it is also the plural of the Latin word “vaccinium,” originally used in English to describe purplish-black berries from a variety of plants. “Vaccinium” nowadays refers to various species of plants, such as Vaccinium myrtillus, bilberries, in the family of Ericaceae, “Hyacinthaceae” is the name given to a different family of plants, and “Hyacinthoides” is the name of a genus of plants in the family Asparagaceae. However, in these cases there may be an etymological connection with “Vaccinium,” via a Cretan form of the Greek name of the youth Hyacinth, whose blood, spilt when he died during a game of quoits with the god Apollo, turned into a plant with purple flowers, thought to be a form of iris or larkspur, but nowadays called hyacinth. Potential medical uses of the pyrrolizidine compound hyacinthacine have been proposed, but, so far at least, its therapeutic applications seem to be less powerful than the myth.

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Acaricidal activity of the hyacinthacine analogues derived from pyrrolizidine alkaloids on Rhipicephalus (Boophilus) microplus

Cited by 5 publications

References 13 publications

Evaluation of medicinal plant extracts against ticks and fluke

Evaluation of medicinal plant extracts against ticks and fluke

Ectoparasiticidal Activity of Herbal Product Keetguard Liquid against Riphicephalus Microplus in Ruminants

When I use a word . . . . Medical hyacinths

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