Açai pulp supplementation as a nutritional strategy to prevent oxidative damage, improve oxidative status, and modulate blood lactate of male cyclists

Fruit-Derived Anthocyanins: Effects on Cycling-Induced Responses and Cycling Performance

“…The effects of anthocyanins on oxidative stress, inflammation, muscle damage, and fatigue were examined in seven studies [ 8 , 11 , 12 , 15 , 17 , 18 , 38 ]. In two studies with trained cyclists equally divided into two groups: Montmorency tart cherry concentrate (MC) (2x − 30 mL + 100 mL of water − 547 mg anthocyanins (ACN) [ 8 ] and 552 mg ACN [ 17 ]) or placebo, differing only in time of supplementation: 7 consecutive days (4 days pre- and on each trial day) [ 8 ] and 8 consecutive days (4 days pre-trial, on the day of, and 3 days post-trial) [ 17 ] cyclists completed a 109 min cycling trial designed to replicate road race demands.…”

“…Açai pulp supplementation was not able to reduce DNA damage, whereas after placebo intervention, an increase in the intensity of the comet tail, assessed by alkaline comet assay, was observed, indicating that there was DNA damage. These results suggest possible prevention of increased DNA damage intensity with açai pulp [ 15 ]. Another study [ 11 ] was carried out with recreationally trained men assigned to drink juçara fruit juice (250 mL − 185 mg ACN) or water (control) 1 h before a high-intensity interval training session.…”

“…The studies that evaluated oxidative stress, inflammation, muscle damage, and fatigue observed improvement of oxidative stress, such as reduced oxidative stress index [ 11 ] and lipid peroxidation [ 8 , 15 ], and increased reduced glutathione [ 11 ], total phenols [ 11 ], uric acid [ 11 ], and TAS [ 12 , 15 ]; inflammation, such as reduced IL-6 [ 8 , 17 ], C-reactive protein [ 38 ], and TNF-α [ 18 ], and increased IL-10 [ 18 ]; muscle damage with creatine kinase reduction [ 38 ]; and fatigue, with lower fatigue [ 11 , 38 ]. These effects were observed in untrained [ 12 ], recreationally trained [ 11 , 18 ], and trained [ 8 , 15 , 17 , 38 ] individuals who performed high-intensity cycling intervals [ 8 , 11 , 17 , 18 ], incremental test [ 15 ], and square-wave endurance test followed by an incremental stress test until exhaustion and a subsequent eccentric exercise [ 38 ].…”

“…Previous evidence has shown that consumption of juices/pulps/powders/extracts derived from anthocyanin-rich fruits, such as cherry, blackcurrant, pomegranate, blueberry, grape, açai, and juçara fruit may have exercise benefits due to a regulation of oxidative stress parameters [ 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ], inflammation [ 8 , 9 , 10 , 15 , 16 , 17 , 18 ], muscle damage [ 8 , 16 , 19 , 20 ], fatigue [ 11 , 21 , 22 ], substrate oxidation [ 12 , 23 , 24 , 25 ], and performance [ 9 , 15 , 18 , 19 , 21 , 22 , 23 , 24 , 26 , 27 , 28 , 29 , 30 ].…”

The Relieving Effects of a Polyherb-Based Dietary Supplement ColonVita on Gastrointestinal Quality of Life Index (GIQLI) in Older Adults with Chronic Gastrointestinal Symptoms Are Influenced by Age and Cardiovascular Disease: A 12-Week Randomized Placebo-Controlled Trial

“…Acai is a phytochemical plant with antioxidant, antiinflammatory, and antigenotoxic effects [32][33][34][35][36]. Dried extract of acai berries improves ethanol-induced ulcer in rats [37].…”