Acacia pennata L. leaves: chemical profiling and impact on DNA damage, alteration of genotoxicity—related genes expression and ROS generation in hepatic tissues of acetaminophen treated male rats

UHPLC‐ESI‐QTOF‐MS2 analysis of Acacia pennata extract and its effects on glycemic indices, lipid profile, pancreatic and hepatorenal alterations in nicotinamide/streptozotocin‐induced diabetic rats

“…According to previous studies, the extracts obtained from A. pennata showed robust antioxidant activity and markedly protected against acetaminophen‐induced reactive oxygen species (ROS) generation in liver tissues of treated rats (EL‐Taher et al, 2021). Consistently, the results from our experiments showed that APE demonstrated antidiabetic and antioxidant properties, suggesting its favorable alleviative effects on ROS and oxidative damage in DM.…”

“…The identification of these classes of compounds in APE is consistent with those of previous studies. For instance, EL‑Taher et al identified the presence of nine flavonoid glycosides (including kaempferol 3,7‐di‐O‐hexoside, apigenin 6,8‐di‐ C ‐hexoside, luteolin‐6‐ C ‐pentoside‐8‐ C ‐hexoside, and apigenin‐6‐ C ‐hexoside‐8‐ C ‐pentoside) from the leaves of A. pennata using LC–ESI–MS analysis (EL‐Taher et al, 2021). In another study, 11 flavonoid glycosides were reported to have been isolated from the aerial parts of A. pennata (Kim et al., 2015).…”

Guava Fruit and Acacia pennata Vegetable Intake Association with Frailty of Older Adults in Northern Thailand

“…Our results were consistent with previous studies that Acacia pennata contained a high content of flavonoid and phenolic compounds [ 46 , 47 ]. Acacia pennata had various biological activities such as anti-nociception against pain [ 48 ], anti-inflammation through inhibition of cyclooxygenases-1 and -2 enzyme activities due to the flavonoid compositions [ 49 ], anti-cancer of pancreas and prostate [ 50 ], prevention of liver damage after acetaminophen-induced genotoxicity [ 51 ], and anti-Alzheimer disease by prevention of β-amyloid aggregation [ 52 ]. In addition, Acacia pennata crude extract at 245 mg/L could kill the larvae and pupae of Aedes aegypti mosquito, which is a potent dengue vector [ 53 ].…”

Slowly Making Sense: A Review of the Two-Step Venom System within Slow (Nycticebus spp.) and Pygmy Lorises (Xanthonycticebus spp.)

“…Supplementary File S1: detailed list of top 100 NCBI BLAST hits on the two chains from BGEsp from N. javanicus , Supplementary File S2: list of all plants slow lorises have been observed eating as well as potential medicinal/toxic effects that may contribute to the venom system and Supplementary File S3: Proposed research agenda for the slow loris venom system. References [ 64 ] are cited in Supplementary File S1 and references [ 56 , 101 , 137 , 138 , 139 , 166 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 ,…”