Abstract:Cocaine use disorder (CUD) continues to be a major public health and social problem with >1.5 million users resulting in 14,556 deaths in 2017 in the United States and with no FDA‐approved medications available (Volkow and Koob, 2016). Preclinical studies in nonhuman primates have shown that monoamine releasers such as amphetamine can reduce the reinforcing strength of cocaine under several schedules of cocaine self‐administration (SA; Czoty et al. 2010; Negus et al. 2003a, b). However, the high abuse poten… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.