Abundance of G-Quadruplex Forming Sequences in the Hepatitis Delta Virus Genomes
Václav Brázda,
Natália Valková,
Michaela Dobrovolná
et al.
Abstract:Hepatitis
delta virus (HDV) is a highly unusual RNA satellite virus
that depends on the presence of hepatitis B virus (HBV) to be infectious.
Its compact and variable single-stranded RNA genome consists of eight
major genotypes distributed unevenly across different continents.
The significance of noncanonical secondary structures such as G-quadruplexes
(G4s) is increasingly recognized at the DNA and RNA levels, particularly
for transcription, replication, and translation. G4s are formed from
guanine-rich seque… Show more
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