Abstract.We used photoionization models in order to reproduce the observed gradients of emission-line ratios for H regions located in the normal spiral galaxy M 101 and in three barred spiral galaxies, namely NGC 1365, NGC 925, and NGC 1073. The behavior of the following nebular parameters across the disk of these galaxies was determined: temperature of the ionizing star (T eff ), ionization parameter (U), and the abundance ratios O/H, N/O, and S/O. Our O/H predictions were found to be consistent with some empirical abundance determinations, but are overestimated by a factor of 0.1−0.4 dex when compared to the direct abundance determinations. NGC 1073 seems to be overabundant in nitrogen compared to other spiral galaxies. No gradient of S/O was found in the studied galaxies, and we derived a positive T eff gradient of T eff / R = (400 ± 112) K kpcand U ranging from −3.0 to −2.3. The N/O vs. O/H diagram in general is consistent with chemical evolution models that assume that the nitrogen synthesis has both a primary and a secondary component compared to oxygen. However, a very strong N/O dependence on the O/H at high abundance was found.