Abstract:Due to the recent rise in immunotherapy research to treat Glioblastoma, immunocompetent mouse models have become increasingly crucial for the study of novel immunotherapies against brain tumors. However, the kinetics of the immune response against the most prevalent immunocompetent GBM models, GL261 and CT2A, have not been well studied, nor have they been compared adequately in the literature. In this study, we compared the immune response in these models using flow cytometry and immunohistochemistry. We inves… Show more
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