Abstract P4-04-14: High mammographic density is associated with deposition of organised fibrillar collagen and increased stiffness in periductal breast stroma
Abstract:Introduction
High mammographic density (MD) in women is strongly associated with breast cancer risk. However the structural and compositional differences between dense and non-dense breast tissues are not well defined. We determined the relationship between MD, collagen deposition and fibril alignment, and tissue micro-stiffness, in similarly aged individuals without adjacent cancer.
Methods
Fresh tissue samples were collected from post-menopausal women undergoing b… Show more
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