Abstract P3-01-15: Significant discordance between clinical and pathological staging in early stage HER2+ and triple negative breast cancers treated with upfront surgery
Abstract:Introduction: Treatment of early-stage human epidermal receptor -2 (HER2) positive and triple negative breast cancer (TNBC) remains a challenge as disease recurrences and subsequent morbidity and mortality continues to be high for these tumors. Current guidelines suggest a neoadjuvant approach with chemotherapy alone (in TNBC’s), or in combination with single or dual HER2 directed therapy (in HER2 + tumors), for all ≥cT2 disease. Standard diagnostic modalities have oftentimes failed to confirm the correct size… Show more
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