Abstract:Background: Local or regional recurrence in breast cancer is associated with poor prognosis. Mastectomy is the classic indication in these situations. However, second attempts of breast conservation in previously radiated patients with small, histologically favorable local relapse have been reported. Also, prospective data (The CALOR Trial) suggest that adjuvant chemotherapy should be recommended in patients with isolated loco-regional recurrence, especially if the recurrence is HR negative. The purpose of our… Show more
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