Abstract:Background:
Breast cancer (BC) is a heterogeneous disease and can be classified according to the expression of four genes: estrogen receptor (ER), progesterone receptor (PGR), human epidermal growth factor receptor 2 (HER2) and marker of proliferation KI67. Four groups of BC have been described: Luminal A (ER+ or PGR+, KI67- HER2-), Luminal B (ER+ or PGR+, KI67+ or HER2+), HER2 (ER- HER2+) and triple negative (ER- PGR- HER2-). Autophagy is a lysosomal degradation pathway which plays a crucial du… Show more
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