2023
DOI: 10.1158/1538-7445.am2023-lb064
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Abstract LB064: Using a genomic only approach to a radiation-age association for supplementing differentiation amongst lung diseases and cancer using PMBCs

Abstract: Purpose: Ionizing radiation may serve as a reference variable to estimating biological age since it mirrors cumulative DNA damage similar to aging processes. To do this, we aim to establish a rad-age association using genomics as its foundation and clinical applicability with lung disease as an overlapping health concern. Methods: Two datasets were combined and used to empirically find the age cutoff between young and old patients: GSE42488 (Data-A1) and GSE53351 (Data-A2). With age as both a ca… Show more

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