Abstract:Prostate cancer is one of the leading causes of cancer-related death among men in the United States due, in part, to its aggressiveness and resistance to therapy following a remission period. Receptor tyrosine kinases are emerging as potential therapeutics in prostate cancer. One of these receptors, the Ron receptor tyrosine kinase, has been shown to be overexpressed in a variety of cancers where it modulates many cellular functions relevant to cancer such as invasion, inflammation, angiogenesis, and prolifera… Show more
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