Abstract:In a multi-disciplinary project, patient derived glioblastoma stem-cell cultures (GSCs) have been established and characterized extensively with the goal of applying computational efforts to integrate results from high-throughput screens of drugs and RNAi with genomic and transcriptional profiling to predict the most successful therapy for individual glioma patients. The main goal of this study was to develop a platform for testing the tumor-initiating capacity of GSCs in mouse brain and to label the cells wit… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.