Abstract 4658: First interim analysis of a randomized study to evaluate safety and efficacy of individualized dendritic cell-based cancer immune therapy for glioblastoma multiforme.
Abstract:The first line treatment for Glioblastoma Multiforme (GBM), surgery, chemo-, and radiotherapy, gains patients little over one year. This makes novel treatment strategies highly warranted. One such strategy is cancer immune therapy (CIT). We conduct a randomised phase II clinical trial using a completely individualised CIT concept based on dendritic cells (DC) for the treatment of GBM. The novel feature of our DC-CIT technology is that exposure to bacterial endotoxins enables DC to prime type 1 T-helper cells, … Show more
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