Abstract:Initial studies of the Odontogenic Ameloblast-Associated Protein (ODAM) revealed that it is highly expressed in mature ameloblasts and is present in the rodent enamel organ and junctional epithelium. Further analysis showed that ODAM is expressed in several epithelial malignancies including gastric, colon, breast, lung and melanoma. A correlation was observed between ODAM expression/localization and breast cancer stage/clinical patient outcome, indicating that ODAM may serve as a novel prognostic biomarker in … Show more
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