Abstract:Previous work demonstrated that poly(vinyl alcohol) (PVA) holds great potential as a cardiovascular biomaterial. PVA prevents thrombosis at least as well as expanded polytetrafluoroethylene (ePTFE) clinical vascular grafts in whole blood studies. However, long term
in vivo
success of this material will likely depend on its ability to support an endothelial cell (EC) monolayer. To promote EC attachment and growth we are treating the PVA surface with high energy reactive ions. We hypothes… Show more
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