Abstract:Age-related prostate diseases are among the most frequently encountered conditions in the male population and age remains a major risk for prostate cancer (PCa) development. Understanding the cellular origins of age-related prostate hyperplasia and dysplasia and finding novel ways to halt progression towards malignancy remain fundamental challenges of PCa treatment, prevention, and patient stratification. Elucidating how aging alters the barriers posed by normal homeostasis to tumor cells expansions is of para… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.