Abstract:Changes in ocular blood flow occur in systemic diseases. A high peak systolic velocity (PSV) in the ophthalmic artery (OA) has been observed in diabetes mellitus and hypertension, conditions often associated with high tissue renin-angiotensin system (RAS) activity and reduced renal plasma flow (RPF). Since our group has demonstrated that sodium restriction (
a high RAS state
) is associated with a decrease in RPF which is correctable with ACE inhibition, we hypothesized that sodium rest… Show more
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