Abstract 285: Integrative analyses of genome-wide expression of miRNAs and DNA methylation patterns in hepatocellular carcinoma to improve functional biomarker identification
Abstract:Previous studies, including ours have examined aberrant expression of microRNAs (miRNAs) and altered DNA methylation, and several miRNAs have been identified as regulated by DNA methylation. However, whether this mechanism occurs at a genome-wide level and is related to the profiles of dysregulated miRNA commonly observed in hepatocellular carcinoma (HCC) patients is largely unknown. Using a two-phase study design, we conducted a genome-wide screening for miRNA expression and DNA methylation profiles in the tu… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.