Abstract 266: Angiotensin I-7 modulates transcriptional (de)activation of multiple members of steroid hormone receptor superfamily: Possible mechanisms underlying inhibited proliferation in (T47D) human breast cancer cells
Abstract:Introduction: Renin Angiotensin System (RAS) is correlated to breast cancer and to other types of cancer. Angiotensin I-7 [Ang-(I-7)] is an endogenous 7-amino acid peptide hormone of this system that has anti-proliferative properties. Interestingly, there are increasing evidences that RAS is implicated in the development of breast cancer. Objectives: We aimed to evaluate the expression of steroid hormone receptors (progesterone receptors (PR), estrogen receptors (ER), androgen receptors (AR), apoptosis and pro… Show more
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