Abstract:The likelihood of developing prostate cancer increases with age; hence with the increasing lifespan of Americans the prevalence of prostate cancer is also increasing. Prostate cancer is responsive to endocrine mediators and while estrogen therapy is a well-known classic treatment regiment for prostate cancer, the inhibition of hedgehog signaling has more recently been reported to be important for prostate cancer therapy. Our lab is interested in the role of hedgehog signaling in prostate cancer development and… Show more
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