Abstract:Introduction:
Acalabrutinib, a next generation Bruton’s tyrosine kinase inhibitor (BTKi) associates with dramatic efficacy against hematology malignancies. Unexplained ventricular arrhythmias (VAs) with next generation BTKi therapy have been reported. Yet, whether acalabrutinib associates with VAs in long-term follow up is unknown.
Methods:
Leveraging a cohort of 290 consecutive hematologic malignancy patients treated with acalabrutinib (2014-2020), we … Show more
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